摘要
由于传统的溴代阻燃剂(brominated flame retardants,BFRs),如多溴二苯醚(PBDEs)和六溴环十二烷(HBCD)等具有较高的生态风险,作为替代物的新型溴代阻燃剂(novel BFRs,NBFRs)被越来越多地生产和使用,如六溴苯(HBB)、五溴甲苯(PBT)、十溴二苯乙烷(DBDPE)、1,2-双(2,4,6-三溴苯氧基)乙烷(BTBPE)、四溴邻苯二甲酸双(2-乙基己基)酯(TBPH)和2,3,4,5,6,-五溴乙苯(PBEB)等。大量的NBFRs的生产、使用和废弃,导致其不可避免地释放到环境中,对生态环境和人类健康造成潜在的威胁。已有研究发现很多NBFRs不仅具有急性毒性、肝脏毒性、内分泌干扰毒性和发育毒性等毒性效应,也具有生物富集、积累和放大效应,存在生态风险。但目前缺乏系统和总结性的研究概述,故基于现有的研究结果,本文综述了有代表性的NBFRs的毒性效应研究内容和问题,并提出今后主要的研究方向。
Since legacy brominated flame retardants(BFRs)like polybrominated flame retardants(PBDEs)and hexabromocyclododecane(HBCD)possessing higher ecological risks,as replacements,novel brominated flame retardants(novel BFRs,NBFRs)are more and more produced and used,such as hexabromobenzene(HBB),pentabromotoluene(PBT),decabromodiphenyl ethane(DBDPE),1,2-bis(2,4,6-tribromophenoxy)ethane(BTBPE),tetrabromophthalate bis(2-ethylhexyl)ester(TBPH),2,3,4,5,6-pentabromoethylbenzene(PBEB),etc.Substantial NBFRs have been inevitably discharged into the environment in the process of generation,application and disposal,threatening the ecological environment and human health.It has been found that many NBFRs not only have toxic effects involving acute toxicity,hepatotoxicity,endocrine disrupting toxicity,and developmental toxicity,but also have bioaccumulation,bioconcentration,and biomagnification resulting in ecological risks.However,due to the lack of systematic and summative review,this review summarizes the research contents and issues of the toxicity and environmental behaviors of representative NBFRs,and then put forward the main future research directions.
作者
王钦
李晨光
尹诗琪
张延蕾
李锋民
Wang Qin;Li Chenguang;Yin Shiqi;Zhang Yanlei;Li Fengmin(Institute of Coastal Environmental Pollution Control,College of Environmental Science and Engineering,Ocean University of China,Qingdao 266100,China;Key Laboratory of Marine Environment and Ecology,Ministry of Education,Ocean University of China,Qingdao 266100,China;Marine Ecology and Environmental Science Laboratory,Qingdao Pilot National Laboratory for Marine Science and Technology,Qingdao 266071,China;Sanya Oceanographic Institution of Ocean University of China,Marine Ecological Environment Protection and Resource Development Center,Sanya 572000,China)
出处
《生态毒理学报》
CAS
CSCD
北大核心
2023年第2期212-223,共12页
Asian Journal of Ecotoxicology
基金
山东省自然科学基金青年项目(ZR2021QD063)
国家自然科学基金资助项目(42207297)
国家重点研发计划项目(2018YFC0406300)
山东省重大科技创新工程(2019JZZY020302)。
关键词
新型溴代阻燃剂
急性毒性
肝脏毒性
内分泌干扰毒性
发育毒性
生态风险
novel brominated flame retardants
acute toxicity
hepatotoxicity
endocrine disrupting toxicity
developmental toxicity
ecological risk
