摘要
目的:观察针刺联合芎芷地龙汤对无先兆性偏头痛患者头痛程度、生活质量及睡眠质量的影响。方法:将60例无先兆性偏头痛患者随机分为阳性药物组(30例,脱落3例)与针药结合组(30例,无脱落)。阳性药物组口服盐酸氟桂利嗪胶囊,每晚1次,每次10 mg。针药结合组采用针刺联合芎芷地龙汤治疗,针刺选穴风池、率谷、百会等,芎芷地龙汤每日2次,每次1袋。两组均治疗4周。观察两组在治疗前、治疗后及随访时偏头痛患者视觉模拟评分(VAS),偏头痛特异性生活质量评分(MSQ)和匹兹堡睡眠质量量表评分(PSQI)。结果:与治疗前比较,两组患者治疗后和随访时VAS、PSQI评分显著降低(P<0.05,P<0.01),MSQ之功能限制和功能障碍评分显著升高(P<0.05,P<0.01),且针药结合组优于阳性药物组(P<0.01,P<0.05);与治疗后比较,针药结合组随访时VAS评分显著升高(P<0.01),MSQ之功能限制和功能障碍评分均显著降低(P<0.05),且针药结合组VAS、PSQI评分均显著低于阳性药物组(P<0.01,P<0.05),MSQ之功能限制评分显著高于阳性药物组(P<0.01)。结论:针药结合可有效改善无先兆性偏头痛患者的头痛程度、生活质量及睡眠质量。
Objective:To observe the effects of acupuncture combined with Xiongzhi Dilong Decoction on the degree of headache,quality of life and sleep quality in patients with migraine without aura.Methods:Sixty migraine patients were randomly divided into positive drug group(30 cases,3 cases of shedding)and needle-drug combination group(30 cases,no shedding).In the positive drug group,flunarizine hydrochloride capsule was administered orally once a night at 10 mg,and in the combination of acupuncture and medicine group,acupuncture was combined with Xiongzhi Dilong Decoction,and acupuncture points such as Feng Chi(GB 20),Shuaigu(GB 8)and Bai Hui(GV 20)were selected,and Xiongzhi Dilong Decoction was administered twice a day at 1 bag each time.Both groups were treated for 4 weeks.The visual analogue score(VAS),migraine specific quality of life score(MSQ)and Pittsburgh sleep quality score(PSQI)of migraine patients before,after treatment and at follow-up were observed in both groups.Results:Compared with pre-treatment,VAS and PSQI scores were significantly lower(P<0.05,P<0.01)and functional limitation and dysfunction scores of MSQ were significantly higher(P<0.05,P<0.01)in both groups after treatment and at follow-up,and the needle-drug combination group was better than the positive drug group(P<0.01,P<0.05);Compared with post-treatment,the VAS score was significantly higher(P<0.01)and the functional limitation and dysfunction scores of MSQ were significantly lower(P<0.05)in the needle-drug combination group at the follow-up,and the needle-drug VAS and PSQI scores were significantly lower in the combination group than in the positive drug group(P<0.01,P<0.05),and functional limitation scores in the MSQ were significantly higher than in the positive drug group(P<0.01).Conclusion:The combination of acupuncture and medicine can effectively improve the headache degree,quality of life and sleep quality of migraine patients.
作者
付勇
廖璐
李琳慧
喻文
黄彪
胡凯玲
颜纯钏
熊俊
刘慧
章海凤
FU Yong;LIAO Lu;LI Lin-hui;YU Wen;HUANG Biao;HU Kai-ling;YAN Chun-chuan;XIONG Jun;LIU Hui;ZHANG Hai-feng(The Affiliated Hospital of Jiangxi University of Chinese Medicine,Nanchang 330006,China;The Graduate School of Jiangxi University of Chinese Medicine,Nanchang 330004,China)
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2023年第6期2961-2964,共4页
China Journal of Traditional Chinese Medicine and Pharmacy
基金
国家重点研发计划(No.2019YFC1709703)
江西省科技厅项目(No.20192ACBL20024,No.20203BBGL73207)。
关键词
无先兆性偏头痛
针药结合
睡眠质量
生活质量
临床研究
Migraine without aura
Acupuncture combined with Chinese medicine
Sleep quality
Quality of life
Clinical study