摘要
目的分析心通颗粒联合比索洛尔治疗急性冠脉综合征合并心力衰竭的疗效。方法方便选取2020年6月—2022年6月邹城市人民医院收治的150例急性冠脉综合征合并心力衰竭患者为研究对象,采用随机分组的方式将其分为对照组(服用比索洛尔)和观察组(服用心通颗粒联合比索洛尔),各75例。对两组患者治疗后的心功能水平、血清炎性因子水平[C-反应蛋白(C-reactive protein,CRP)、降钙素原(procalcitonin,PCT)、白细胞介素-6(interleukin-6,IL-6)]、凝血指标以及心绞痛控制情况进行比较分析。结果治疗4周后,观察组LVEF高于对照组,LVESD、GLS、TLS、LVEDD均低于对照组,差异有统计学意义(P<0.05)。观察组治疗后PCT、CRP、IL-6水平均低于对照组,差异有统计学意义(t=45.560、7.109、15.233,P<0.05)。观察组治疗后心绞痛稳定指数高于对照组,心绞痛发作指数低于对照组,差异有统计学意义(P<0.05)。观察组治疗后PT、ARTT值高于对照组,PAR、FIB值低于对照组,差异有统计学意义(P<0.05)。结论心通颗粒联合比索洛尔治疗急性冠脉综合征合并心力衰竭患者的疗效更好,患者在经过治疗后,心功能水平及凝血指标更优,机体炎性因子水平更低,心绞痛等症状控制更好。
Objective To analyze the efficacy of Xintong granules combined with bisoprolol in the treatment of acute coronary syndrome combined with heart failure.Methods 150 patients with acute coronary syndrome complicated with heart failure who were admitted to Zoucheng People's Hospital from June 2020 to June 2022 were conveniently selected as research objects.All patients were randomly divided into control group(taken bisoprolol)and observation group(taken Xintong Granules combined with bisoprolol),75 patients in each group.The cardiac function level,serum inflammatory factor levels[C-reactive protein(CRP),calcitonin(PCT),interleukin-6(IL-6)],coagulation indexes and angina control were compared between the two groups after treatment.Results After 4 weeks of treatment,the LVEF of the observation group was higher than that of the control group,and the LVESD,GLS,TLS,and LVEDD scores were lower than those of the control group,the difference was statistically significant(P<0.05).After treatment,the PCT,CRP,and IL-6 levels in the observation group were significantly lower than those in the control group,the difference was statistically significant(t=45.560,7.109,15.233,P<0.05).After treatment,the stability index of angina pectoris in the observation group was higher than that in the control group,and the angina attack index was lower than that in the control group,the difference was statistically significant(P<0.05).After treatment,the PT and ARTT values in the observation group were higher than those in the control group,while the PAR and FIB values were lower than those in the control group,the difference was statistically significant(P<0.05).Conclusion The combination of Xintong Granules and Bisoprolol has a better therapeutic effect on patients with acute coronary syndrome combined with heart failure.After treatment,patients have better levels of cardiac function and coagulation indicators,lower levels of inflammatory factors,and better control of symptoms such as angina.
作者
袁玉香
袁永红
YUAN Yuxiang;YUAN Yonghong(Department of Cardiology,Zoucheng People's Hospital,Jining,Shandong Province,273500 China;Department of Cardiology,Yankuang New Journey General Hospital,Jining,Shandong Province,273500 China)
出处
《中外医疗》
2023年第17期140-144,共5页
China & Foreign Medical Treatment
关键词
心通颗粒
比索洛尔
急性冠脉综合征
心力衰竭
对比治疗
Xintong granules
Bisoprolol
Acute coronary syndrome
Heart failure
Comparative treatment
