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宫腹腔镜联合辅助生殖技术治疗不孕不育症的有效性研究 被引量:3

Study on the Effectiveness of Hysteroscopy Laparoscopy Combined with Assisted Reproductive Technology in the Treatment of Infertility
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摘要 目的观察分析宫腹腔镜联合辅助生殖技术治疗不孕不育症的临床价值。方法随机选择2020年3月—2021年3月在山东国欣颐养集团枣庄医院就诊的50例不孕不育症患者为研究对象,运用抽签法将其分为两组,各25例,参照组用宫腹腔镜手术,优化组应用宫腹腔镜联合辅助生殖技术治疗,对比两组患者的黄体生成素(LH)、雌激素(E_(2))、卵泡刺激素(FSH)水平,各项临床指标和并发症情况以及受孕率。结果术前,两组患者的LH、E_(2)、FSH水平比较,差异无统计学意义(P>0.05);术后3个月,优化组患者的LH、E_(2)、FSH均高于参照组,差异有统计学意义(P<0.05)。优化组患者的手术时间、术中出血量、首次下床时间低于参照组,差异有统计学意义(P<0.05)。优化组的并发症发生率(8.00%)低于参照组(36.00%),差异有统计学意义(χ^(2)=5.710,P<0.05)。优化组的受孕率(96.00%)高于参照组(72.00%),差异无统计学意义(χ^(2)=3.720,P>0.05)。结论行宫腹腔镜联合辅助生殖技术治疗效果显著,可改善患者雌激素水平,降低并发症的发生。 Objective To observe and analysis the clinical value of hysteroscopic laparoscopy combined with assisted reproductive technology in the treatment of infertility.Methods 50 infertility patients who were treated in Zaozhuang Hospital of Shandong Guoxin Yiyang Group from March 2020 to March 2021 were randomly selected as the research objects.Based on lottery,the patients were divided into two groups with 25 cases in each group.The reference group was treated with hystero-laparoscopic surgery,and the optimized group was treated with hystero-laparoscopic surgery combined with assisted reproductive technology.The levels of luteinizing hormone(LH),estrogen(E_(2)),follicle stimulating hormone levels(FSH),various clinical indicators,complications,and pregnancy rates were compared between the two groups of patients.Results Before surgery,there was no statistically significant difference in the levels of LH,E_(2),and FSH between the two groups of patients(P>0.05).Three months after operation,the levels of LH,E_(2),and FSH in the optimized group were significantly higher than those in the control group,and the difference was statistically significant(P<0.05).The surgical time,intraoperative bleeding,and first time out of bed of the optimization group patients were lower than those of the control group,and the difference was statistically significant(P<0.05).The incidence of complications in the optimization group(8.00%)was lower than that in the control group(36.00%),and the difference was statistically significant(χ^(2)=5.710,P<0.05).The pregnancy rate of the optimization group(96.00%)was higher than that of the control group(72.00%),and the difference was not statistically significant(χ^(2)=3.720,P>0.05).Conclusion Hysteroscopic laparoscopy combined with assisted reproductive technology has a significant therapeutic effect,which can improve the patient′s estrogen level,and reduce the occurrence of complications.
作者 孙垣芳 李黎明 褚龙 SUN Yuanfang;LI Liming;CHU Long(Department of Obstetrics and Gynecology,Zaozhuang Hospital of Shandong Guoxin Yiyang Group,Zaozhuang,Shandong Province,277100 China;Seventh Department of Internal Medicine,Zaozhuang Hospital of Shandong Health Group,Zaozhuang,Shandong Province,277100 China)
出处 《中外医疗》 2023年第18期90-93,共4页 China & Foreign Medical Treatment
关键词 宫腹腔镜 辅助生殖技术 联合治疗 不孕不育 Uterine laparoscopy Assisted reproductive technology Combined therapy Infertility
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