摘要
目的分析妊娠期糖尿病患者糖尿病葡萄糖耐量试验(diabetes glucose tolerance test,OGTT)不同时间点血糖异常的妊娠结局。方法回顾性选取2020年2月—2022年2月山东省临沂市兰山区人民医院收治的妊娠期糖尿病患者270例为研究对象,依据孕24~28周行75 g OGTT不同时间点血糖异常情况分为1项血糖异常组(124例)、2项血糖异常组(90例)、3项血糖异常组(56例)。统计分析3组血糖与胰岛素水平、血糖控制效果、妊娠结局、新生儿结局。结果与2型血糖异常组、3项血糖异常组相比,1项血糖异常组患者的空腹血糖、餐后1 h血糖、餐后2 h血糖、空腹胰岛素水平、胰岛素抵抗指数均较低,差异有统计学意义(P<0.05)。1项血糖异常组患者饮食运动下空腹血糖、餐后1 h血糖、餐后2 h血糖水平均较低,自然分娩率较高,剖宫产率较低,阴道助产率较低,差异有统计学意义(P<0.05)。1项血糖异常组患者羊水污染、胎膜早破、子痫前期、产后出血、巨大儿、新生儿黄疸、新生儿肺炎、新生儿窒息、新生儿低血糖发生率均较低,差异有统计学意义(P<0.05)。结论妊娠期糖尿病OGTT不同时间点血糖异常项目越多,妊娠结局越差。
Objective To analyze the pregnancy outcome of abnormal blood glucose at different time points in patients with gestational diabetes mellitus during diabetes glucose tolerance test(OGTT).Methods 270 patients with gestational diabetes admitted to Lanshan District People's Hospital,Linyi City,Shandong Province from February 2020 to February 2022 were retrospectively selected as the study subjects.According to the abnormal blood glucose at different time points during 75 g OGTT at 24-28 weeks of pregnancy,they were divided into three groups:one abnormal blood glucose group(124 cases),two abnormal blood glucose groups(90 cases),and three abnormal blood glucose groups(56 cases).Statistical analysis of blood glucose and insulin levels,blood glucose control effects,pregnancy outcomes,and neonatal outcomes in three groups.Results Compared with the type 2 abnormal blood glucose group and the three abnormal blood glucose groups,the Glucose test fasting blood sugar,postprandial blood glucose 1 hour,postprandial blood glucose 2 hours,fasting insulin level,and insulin resistance index of the patients in the one abnormal blood glucose group were lower,and the difference was statistically significant(P<0.05).The level of fasting blood sugar,blood glucose 1 hour after meal,and blood glucose 2 hours after meal in patients with one item of abnormal blood glucose group were lower under diet exercise,the rate of natural childbirth was higher,the rate of cesarean section was lower,and the rate of vaginal delivery was lower,the difference was statistically significant(P<0.05).The incidence of amniotic fluid pollution,premature rupture of membranes,pre eclampsia,Postpartum bleeding,macrosomia,Neonatal jaundice,neonatal pneumonia,neonatal asphyxia,and neonatal hypoglycemia in the patients with one item of abnormal blood glucose group were lower,and the difference was statistically significant(P<0.05).Conclusion The more abnormal blood glucose items at different time points in OGTT of gestational diabetes mellitus,the worse the pregnancy outcome.
作者
王波君
WANG Bojun(Department of Obstetrics and Gynecology,Lanshan District People's Hospital,Linyi,Shandong Province,276000 China)
出处
《糖尿病新世界》
2023年第8期23-27,共5页
Diabetes New World Magazine
关键词
妊娠期糖尿病
OGTT
不同时间点
血糖异常
妊娠结局
新生儿结局
Gestational diabetes mellitus
OGTT
Different time points
Abnormal blood glucose
Pregnancy outcome
Neonatal outcome
