摘要
目的探索广泛性焦虑障碍的中医核心精神症状与中医核心躯体症状,并分析症状间的关系。方法收集500例广泛性焦虑障碍患者的临床症状,采用网络分析方法对中医核心精神症状、中医核心躯体症状、中医核心精神症状与躯体症状关系、中医核心精神症状与中医核心躯体症状关系进行分析。结果广泛性焦虑障碍的中医核心精神症状是善恐易惊、善思、早醒和易激动;中医核心躯体症状是腰痛、胸闷、神疲乏力和口苦;中医核心精神症状与躯体症状研究提示善恐易惊与神疲乏力、善思与心悸、易激动与自汗、早醒与腰痛关联性较强。中医核心精神症状与中医核心躯体症状整合网络分析提示易激动和善思在整个网络中对其他症状影响较大,更多地参与症状间互动,且具有预测其他症状的作用。结论广泛性焦虑障碍与肾、心、肝关系密切,临床治疗应以精神症状为主进行辩证。
Objective To explore the core mental and physical symptoms of generalized anxiety disorder(GAD)in the view of traditional Chinese medicine and analyze the relationship between the symptoms.Methods We collected the clinical symptoms of 500 patients with GAD,and used network analysis method to analyze the core mental symptoms,core physical symptoms,core mental and physical symptoms,and core mental and physical symptoms in the view of traditional Chinese medicine.Results The core mental symptoms of GAD were as follow:prone to be frightened and afraid,overthinking,early awakening,and agitation.The core physical symptoms were as follow:low back pain,chest tightness,tired and weak spirit,and bitter mouth.Studies on core mental symptoms and physical symptoms suggested that there was a strong correlation between prone to be frightened and afraid and the tired and weak spirit,overthinking and palpitations,agitation and spontaneous sweating,early awakening and low back pain.The integrated network analysis of the core mental symptoms and core physical symptoms suggested that agitation and overthinking had a greater impact on other symptoms throughout the network.Conclusions GAD is closely related to the kidney,heart,and liver,and clinical treatment should be focused on dialectical treatment of mental symptoms.
作者
李雪
冯正田
郑思思
段宇航
吴子遥
朱虹
贾竑晓
Li Xue;Feng Zhengtian;Zheng Sisi;Duan Yuhang;Wu Ziyao;Zhu Hong;Jia Hongxiao(The National Clinical Research Center for Mental Disorders&Beijing Key Laboratory of Mental Disorders,Beijing Anding Hospital,Capital Medical University,Beijing 100088,China;Advanced Innovation Center for Human Brain Protection,Capital Medical University,Beijing 100069,China)
出处
《首都医科大学学报》
CAS
北大核心
2023年第4期568-577,共10页
Journal of Capital Medical University
基金
北京市医院管理中心临床医学发展专项(ZYLX202129)
北京市医院管理中心“登峰”人才培养计划项目(DFL20191901)
高层次公共卫生技术人才建设项目培养计划项目(学科骨干-02-40)。
关键词
广泛性焦虑障碍
网络分析
核心精神症状
肾阴虚
generalized anxiety disorder
network analysis
core mental symptoms
kidney-yin deficiency
