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妊娠期亚临床甲状腺功能减退症对脐动脉血流动力学指标与妊娠结局的影响

Influence of subclinical hypothyroidism in pregnancy on hemodynamic indexes of umbilical artery and pregnancy outcome
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摘要 目的探讨妊娠期亚临床甲状腺功能减退症(SCH)对脐动脉血流动力学指标与妊娠结局的影响。方法选取本院1000名建档并分娩的孕妇为研究对象,依据甲状腺功能检查结果分为SCH组(n=150)和非SCH组(n=850)。比较两组不良妊娠结局发生情况及脐动脉血流动力学指标。结果SCH组不良妊娠结局发生率为76.67%,显著高于非SCH组的21.65%(P<0.05);孕晚期SCH组脐动脉阻力指数、搏动指数、收缩末期峰值与舒张末期峰值比值明显高于非SCH组(P<0.05)。结论妊娠期SCH的脐动脉血流动力学指标明显升高,容易影响母胎血流循环状态,导致不良妊娠结局,临床上应加强检测脐动脉血流动力学指标,以改善预后。 Objective To investigate the effect of subclinical hypothyroidism(SCH)on umbilical artery hemodynamics and pregnancy outcome.Methods 1000 pregnant women who were registered and delivered in our hospital were selected as the research subjects.They were divided into the SCH group(n=150)and the non SCH group(n=850)based on the results of thyroid function tests.The adverse pregnancy outcome and umbilical artery hemodynamics were compared between the two groups.Results The incidence of adverse pregnancy outcomes in the SCH group was 76.67%,significantly higher than 21.65%in the non SCH group(P<0.05);Umbilical artery resistance index,pulsatility index,ratio of end systolic peak to end diastolic peak in the third trimester SCH group were significantly higher than those in the non SCH group(P<0.05).Conclusion The hemodynamic indexes of umbilical artery in pregnancy with SCH are significantly increased,which is easy to affect the maternal fetal blood circulation and lead to adverse pregnancy outcomes.It is necessary to strengthen the detection of hemodynamic indexes of umbilical artery in clinical practice to improve the prognosis.
作者 魏苇 韦荣显 侯国英 Wei Wei;Wei Rongxian;Hou Guoying(Department of Function,Hechi Third People's Hospital,Hechi 547000,China)
出处 《实用妇科内分泌电子杂志》 2023年第7期15-17,共3页 Electronic Journal of Practical Gynecological Endocrinology
基金 河池市科技计划项目(编号2021AB42107)。
关键词 妊娠期亚临床甲状腺功能减退症 脐动脉血流动力学 妊娠结局 Subclinical hypothyroidism during pregnancy Umbilical artery hemodynamics Pregnancy outcome
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