摘要
目的探究肾功能指标和尿微量蛋白在早期糖尿病肾病中的应用价值。方法选取2021年4月—2022年6月龙岩市中医院收治的200例糖尿病患者为观察组,其中单纯糖尿病患者110例(A组)、早期糖尿病肾病患者90例(B组),并以同时期的82例健康体检者为对照组,均接受肾功能指标和尿微量蛋白测定,记录血清肌酐(Scr)、血尿素氮(BUN)、血清胱抑素(CysC)、尿微量白蛋白(U-mALB)水平。结果观察组CysC、BUN、Scr及U-mALB水平均高于对照组,差异有统计学意义(P<0.05)。A组CysC、BUN、Scr及U-mALB水平均高于对照组,差异有统计学意义(P<0.05)。B组CysC、BUN、Scr及U-mALB水平均高于A组,差异有统计学意义(P<0.05)。结论CysC、BUN、Scr及U-mALB水平可作为早期糖尿病肾病患者的敏感指标,有助于医生准确掌握患者病情变化,拟定针对性治疗方案,对改善患者预后有重要意义。
Objective To explore the application value of renal function index and urinary microprotein in early diabetic nephropathy.Methods 200 patients with diabetes admitted to Longyan Hospital of Traditional Chinese Medicine from April 2021 to June 2022 were selected as the observation group,including 110 patients with simple diabetes(Group A),90 patients with early diabetes nephropathy(Group B),and 82 healthy people in the same period were selected as the control group.All of them received the determination of renal function indicators and urinary microprotein,and recorded serum creatinine(Scr),blood Blood urea nitrogen(BUN),serum Cystatin(CysC)urinary microalbumin(U-mALB)levels.Results The levels of CysC,BUN,Scr,and U-mALB in the observation group were higher than those in the control group,the difference was statistically significant(P<0.05).The levels of CysC,BUN,Scr,and U-mALB in Group A were higher than those in the control group,the difference was statistically significant(P<0.05).The levels of CysC,BUN,Scr,and U-mALB in Group B were higher than those in group A,the difference was statistically significant(P<0.05).Conclusion CysC,BUN,Scr and U-mALB levels can be used as sensitive indicators for patients with early diabetes nephropathy,which are helpful for doctors to accurately grasp the changes of patients'conditions,formulate targeted Sex therapy programs,and improve the prognosis of patients.
作者
江炜炜
嵇美霞
蒋磊
JIANG Weiwei;JI Meixia;JIANG Lei(Department of Laboratory,Longyan Hospital of Traditional Chinese Medicine,Longyan,Fujian Province,364000 China;Department of Endocrinology,Longyan Hospital of Traditional Chinese Medicine,Longyan,Fujian Province,364000 China)
出处
《糖尿病新世界》
2023年第10期45-48,共4页
Diabetes New World Magazine
关键词
肌酐
血尿素氮
血清胱抑素
尿微量蛋白
早期糖尿病肾病
诊断价值
Creatinine
Blood urea nitrogen
Serum cystatin
Urinary microprotein
Early diabetic nephropathy
Diagnostic value
