摘要
目的分析麦角新碱联合缩宫素对剖宫产产妇产后出血的预防效果。方法选择2021年1月至2021年12月在睢县妇幼保健院接受治疗的102例临产剖宫产产妇作为研究对象。依据随机数字表的方法对入组的产妇实施分组,分为对照组(n=51)及观察组(n=51)。对照组产妇选择缩宫素与卡前列素氨丁三醇联合使用,观察组产妇选择缩宫素与麦角新碱联合使用。比较两组产妇的产后出血发生率、不良反应发生情况、产后2 h及产后24 h的出血量。比较手术前后,两组产妇的血红蛋白和凝血指标(凝血酶时间、凝血酶原时间、纤维蛋白原)、血氧饱和度及心率。结果观察组产妇的产后出血发生率低于对照组,差异有统计学意义(P<0.05)。观察组产妇的不良反应发生率低于对照组,差异有统计学意义(P<0.05)。观察组产妇在产后2 h及产后24 h的出血量均低于对照组,差异有统计学意义(P<0.05)。两组产妇手术前1 d的血红蛋白、凝血酶时间、凝血酶原时间、纤维蛋白原比较,差异无统计学意义(P>0.05)。在手术后1 d,两组产妇的血红蛋白、纤维蛋白原含量均明显低于手术前,凝血酶时间、凝血酶原时间短于手术前,且观察组产妇的血红蛋白含量明显高于对照组,凝血酶时间、凝血酶原时间短于对照组,纤维蛋白原含量明显低于对照组,差异有统计学意义(P<0.05)。两组产妇手术前1 d及手术后1 d的血氧饱和度和心率比较,差异无统计学意义(P>0.05)。结论针对剖宫产产妇使用麦角新碱联合缩宫素,可以有效降低产妇产后出血发生率及不良反应的风险,减少产妇术后的失血量,改善凝血功能及血红蛋白水平,且不会干扰心率及血氧饱和度的水平。
Objective To analyze the preventive effect of ergometrine combined with oxytocin on postpartum bleeding in caesarean section women.Methods From January 2021 to December 2021,102 parturient undergoing caesarean section in Sui County Maternal and Child Health Hospital were selected as the study subjects.According to the method of random number table,the enrolled postpartum women were divided into a control group(n=51)and an observation group(n=51).The control group chose oxytocin combined with carboprost tromethamine,and the observation group chose oxytocin combined with ergometrine.The incidence of postpartum bleeding,the incidence of adverse reactions,and the amount of bleeding 2 hours and 24 hours after delivery were compared between the two groups.Hemoglobin,coagulation index(thrombin time,prothrombin time,fibrinogen),blood oxygen saturation and heart rate were compared between the two groups before and after operation.Results The incidence of postpartum bleeding in the observation group was lower than that in the control group,the difference was statistically significant(P<0.05).The incidence of adverse reactions in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).The bleeding volume of the observation group's postpartum women at 2 hours and 24 hours was lower than that of the control group,with a statistically significant difference(P<0.05).There was no significant difference in hemoglobin,thrombin time,prothrombin time and fibrinogen between the two groups 1 day before operation(P>0.05).On the first day after the operation,the hemoglobin and fibrinogen contents of the two groups were significantly lower than those before the operation,the thrombin time and prothrombin time were shorter than those before the operation,and the hemoglobin content of the observation group was significantly higher than that of the control group,the thrombin time and prothrombin time were shorter than that of the control group,and the fibrinogen content was significantly lower than that of the control group,with statistical significance(P<0.05).There was no statistically significant difference in blood oxygen saturation and heart rate between the two groups of postpartum women 1 day before and 1 day after surgery(P>0.05).Conclusions The use of ergometrine combined with oxytocin for caesarean section women can effectively reduce the incidence of postpartum bleeding and the risk of adverse reactions,reduce the amount of blood loss after operation,improve the coagulation function and hemoglobin level,and will not interfere with the level of heart rate and blood oxygen saturation.
作者
徐盼盼
XU Panpan(Department of Obstetrics and Gynecology,Sui Country Maternal and Child Health Hospital,Shangqiu Henan 476900,China)
出处
《临床研究》
2023年第8期39-41,共3页
Clinical Research
关键词
麦角新碱
缩宫素
剖宫产
产后出血
卡前列素氨丁三醇
ergometrine
oxytocin
caesarean section
postpartum bleeding
carboprost tromethamine
