摘要
目的探讨去甲肾上腺素复合丙泊酚、依托咪酯在无痛胃肠镜检查中的应用效果。方法选择阜阳民生医院2021年1月至2022年3月行无痛胃肠镜检查的患者60例,按随机数字表法分为研究组和对照组,每组30例。对照组给予0.1 mg/kg依托咪酯+1~2 mg/kg丙泊酚静脉注射;研究组给予0.1 mg/kg依托咪酯+1~2 mg/kg丙泊酚+0.83μg/mL去甲肾上腺素静脉注射。比较两组患者胃肠镜检查时间、恢复室停留时间和苏醒时间,满意度情况,观察并记录麻醉诱导前(T0)、麻醉诱导后5 min(T1)和唤醒时(T2)的血流动力学指标[包括收缩压、舒张压、心率(HR)和脉搏血氧饱和度(SpO_(2))],以及不良反应发生情况。结果研究组患者苏醒时间短于对照组(P<0.05);两组患者胃肠镜检查时间和恢复室停留时间比较差异均无统计学意义(均P>0.05)。研究组患者满意度评分(9.34±0.58)分,高于对照组的(8.95±0.47)分(P<0.05)。两组患者T1和T2时点收缩压、舒张压、HR和SpO_(2)均低于T0时点(均P<0.05);研究组患者T1和T2时点收缩压、舒张压、HR和SpO_(2)均高于对照组(均P<0.05)。研究组不良反应发生率为20.0%,对照组不良反应发生率为13.3%,两组患者不良反应发生率比较差异无统计学意义(P>0.05)。结论去甲肾上腺素复合丙泊酚、依托咪酯在无痛胃肠镜检查中的应用效果良好,患者血流动力学指标平稳,麻醉并发症发生率低,患者满意度较高。
Objective To investigate the efficacy of norepinephrine combined with propofol and etomidate in painless gastroenteroscopy.Methods Sixty patients who underwent painless gastroenteroscopy at Fuyang Minsheng Hospital from January 2021 to March 2022 were randomly divided into a study group and a control group with 30 cases in each group.The control group was given 0.1 mg/kg etomidate+1-2 mg/kg propofol intravenously before gastroenteroscopy;the study group was given 0.1 mg/kg etomidate+1-2 mg/kg propofol+0.83μg/mL norepinephrine intravenously.The gastroenteroscopy time,recovery room stay time,recovery time,satisfaction,hemodynamic indicators at preanesthesia induction(T_(0)),5 min after anesthesia induction(T_(1)),and awakening(T_(2)),the systolic blood pressure,diastolic blood pressure,heart rate(HR),and blood oxygen saturation(SpO_(2))and adverse reactions were compared between the two groups.Results The recovery time of the study group was shorter than that of the control group(P<0.05).There were no statistically significant differences in endoscopic examination time and recovery room stay time between two groups(both P>0.05).The satisfaction score of patients in the study group(9.34±0.58)was higher than that in the control group(8.95±0.47)(P<0.05).The systolic blood pressure,diastolic blood pressure,HR,and SpO_(2)of the two groups of patients at T_(1)and T_(2)were lower than those at T_(0)(all P<0.05).The systolic blood pressure,diastolic blood pressure,HR,and SpO_(2)of the study group patients at T_(1)and T_(2)were higher than those of the control group(P<0.05).There was no significant incidence in adverse reactions between two groups(20.0%vs.13.3%,P>0.05).Conclusion The application of norepinephrine combined with propofol and etomidate in painless gastroenteroscopy has a good efficacy,which can speed up the recovery of patients,improve patient satisfaction,and has little impact on hemodynamics.
作者
阮玉琴
唐天奇
RUAN Yuqin;TANG Tianqi(Department of Anesthesiology,Fuyang Minsheng Hospital,Fuyang 236000,China;不详)
出处
《浙江医学》
CAS
2023年第13期1416-1419,共4页
Zhejiang Medical Journal
