摘要
Dear Editor,The ion channel transient receptor potential melastatin-like 7(TRPM7)has a serine-threonineα-kinase domain(M7CK)on its intracellular C-terminal[1,2].In cell lines,M7CK is cleaved and translocated to the nucleus to regulate a variety of cellular processes including cell proliferation and survival[3].In neuroblastoma cells.
基金
supported by the National Natural Science Foundation of China(31970942 and 81573408)
the Shanghai Municipal Science and Technology Major Project(2018SHZDZX01)
the ZJ Lab,and Shanghai Center for Brain Science and Brain-Inspired Technology.