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TRPM7 Kinase Domain is Part of the Rac1-SSH2-cofilin Complex Regulating F-actin in the Mouse Nervous System

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摘要 Dear Editor,The ion channel transient receptor potential melastatin-like 7(TRPM7)has a serine-threonineα-kinase domain(M7CK)on its intracellular C-terminal[1,2].In cell lines,M7CK is cleaved and translocated to the nucleus to regulate a variety of cellular processes including cell proliferation and survival[3].In neuroblastoma cells.
出处 《Neuroscience Bulletin》 SCIE CAS CSCD 2023年第6期989-993,共5页 神经科学通报(英文版)
基金 supported by the National Natural Science Foundation of China(31970942 and 81573408) the Shanghai Municipal Science and Technology Major Project(2018SHZDZX01) the ZJ Lab,and Shanghai Center for Brain Science and Brain-Inspired Technology.
关键词 RAC1 SSH2 NEUROBLASTOMA
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