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赶黄草本草考证、化学成分和药理作用研究 被引量:1

Herbal Textual Research,Chemical Components and Pharmacological Effects of Penthorum Chinense
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摘要 本文通过查阅历代草本书籍文献,从名称、形态、采收加工、分布区域及功效方面对赶黄草进行本草考证,并对其化学成分和药理作用进行梳理和归纳,为赶黄草的进一步研究与应用提供依据。研究发现赶黄草为正名,其余可作为别名;历代草本文献对原植物形态描述基本一致;夏、秋二季采收,药用部位为全草入药,加工方法为除去杂质,干燥或趁鲜切段;广泛分布于我国东北、华北、华东、华南和西南等地;主要成分为黄酮(苷)、三萜(苷)类及甾体类、挥发油等;具有抗肝纤维化、保肝等药理活性,并有改善肾功能、降血糖等潜在药用价值。目前,赶黄草尚无本草考证相关研究,同物异名现象严重,未被收入《中华人民共和国药典》,地方标准和炮制方法不统一。今后需要加强相关研究,提高和统一质量标准,开发新应用。 To provide basis for the further research and application of Penthorum chinense,herbal textual research was carried out on the Penthorum chinense from the aspects of name,shape,collection and processing,distribution area and efficacy through consulting the herbal books and literature,and the chemical components and pharmacological effects were sorted and summarized.It was found that Penthorum chinense was the rectification of name,and the rest could be used as aliases.The description of the plant morphology was basically consistent in the herb literature of the past dynasties.Penthorum chinense was harvested in summer and autumn.The medicinal part was the whole herb,and the processing method was to remove impurities,then dry or cut while fresh.Penthorum chinense was widely distributed in Northeast China,North China,East China,South China,Southwest China and other places.The main components were flavonoids(glycosides),triterpenoids(glycosides),steroids and volatile oils.Penthorum chinense had pharmacological activities such as anti-liver fibrosis,liver protection,besides,it had potential medicinal value such as improving renal function and lowering blood sugar.At present,there is no relevant research on the herbal textual research,and the phenomenon of synonyms is serious.It is not included in the Chinese Pharmacopoeia,and the local standards and processing methods are not unified.In the future,it is necessary to strengthen the relevant research,improve and unify the quality standards,and develop new applications.
作者 袁晓明 胡丹 YUAN Xiaoming;HU Dan(Dept.of Chemistry,Food and Drug Testing Center of Anhui Suzhou,Anhui Suzhou 234000,China)
出处 《中国医院用药评价与分析》 2023年第7期889-891,896,共4页 Evaluation and Analysis of Drug-use in Hospitals of China
基金 安徽省中药材标准研究课题(No.AHYJ-YP056-2022) 安徽省药品监督管理局科技创新项目(No.AHYJ-KJ-202220)。
关键词 赶黄草 本草考证 化学成分 药理作用 Penthorum chinense Herbal textual research Chemical components Pharmacological effects
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