摘要
目的:探究类风湿因子(RF)、红细胞沉降率(ESR)、C反应蛋白(CRP)、抗环状瓜氨酸抗体(Anti-CCP)四项血清学指标在类风湿关节炎(RA)诊断中的临床价值。方法:选取2021年4月—2023年2月盘锦市中心医院收治的RA患者30例作为观察组,其他免疫疾病患者30例作为对照组,健康体检者30例作为正常组。比较对照组与观察组RF、ESR、CRP及Anti-CCP血清学指标水平差异,观察组与正常组RF、ESR、CRP及Anti-CCP血清学指标水平差异。结果:观察组患者RF、ESR、CRP及Anti-CCP血清学指标水平均高于对照组,差异有统计学意义(P<0.001);观察组患者RF、ESR、CRP及Anti-CCP血清学指标水平均高于正常组,差异有统计学意义(P<0.001)。结论:对于RA患者而言,在其诊断过程中注重四项血清学指标(RF、ESR、CRP、Anti-CCP)有助于了解疾病的具体情况,进而协助患者获取针对性治疗,降低疾病所带来的风险,为治疗方案的制定与调整提供可靠依据。
Objective:To explore the clinical value of rheumatoid factor(RF),erythrocyte sedimentation rate(ESR),C-reactive protein(CRP)and anti-cyclic citrulline antibody(Anti-CCP)in the diagnosis of rheumatoid arthritis(RA).Methods:Thirty RA patients admitted to Panjin Central Hospital from April 2021 to February 2023 were selected as the observation group,thirty patients with other immune diseases as the control group,and thirty healthy physical examination subjects as the normal group.The serum levels of RF,ESR,CRP and Anti-CCP were compared between control group and observation group,and the serum levels of RF,ESR,CRP and Anti-CCP were compared between observation group and normal group.Results:Serological indexes of RF,ESR,CRP and Anti-CCP in observation group were higher than those in control group,with statistical significance(P<0.001).Serological indexes of RF,ESR,CRP and Anti-CCP in observation group were higher than those in normal group,and the differences were statistically significant(P<0.001).Conclusion:For patients with RA,focusing on the four serological indicators(RF,ESR,CRP,and Anti-CCP)in the diagnosis process can help to understand the specific condition of the disease,and then assist patients to obtain targeted treatment,reduce the risk of the disease,and provide a reliable basis for the formulation and adjustment of treatment plans.
作者
张素英
Zhang Suying(Department of Laboratory,Panjin Central Hospital,Panjin 124010,Liaoning Province,China)
出处
《中外医药研究》
2023年第7期132-134,共3页
JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH
关键词
类风湿性关节炎
类风湿因子
红细胞沉降率
C反应蛋白
抗环状瓜氨酸抗体
Rheumatoid arthritis
Rheumatoid factor
Erythrocyte sedimentation rate
C-reactive protein
Anti-cyclic citrulline antibody
