摘要
目的探讨前列腺动脉栓塞术(PAE)治疗前列腺增生(PH)的临床疗效和安全性。方法选取PH患者70例,随机分为对照组(35例)和治疗组(35例)。其中对照组行尿道前列腺等离子电切除术,治疗组行PAE。比较两组患者临床疗效和康复程度差异,记录两组患者手术时间、术中出血量、尿管留置时间、术后住院时间和并发症情况;记录两组患者手术前后的最大尿流率(Qmax)、残余尿量(RUV)、生活质量评分(QOL)、国际前列腺症状评分(IPSS)、前列腺体积(PV)、血流动力学指标以及检测炎性指标。结果治疗组临床总有效率为91.43%高于对照组85.71%。治疗组手术时间、术中出血量、尿管留置时间、术后住院时间和并发症情况低于对照组,且差异有统计学意义(均P<0.001)。治疗组中术后3个月患者Qmax、RUV、QOL、IPSS和PV均明显优于对照组(均P<0.01)。此外,治疗组中血流动力学和炎性相关指标的改善程度均优于对照组(P<0.05,P<0.01)。结论临床采用PAE治疗PH患者疗效显著,明显改善了患者前列腺功能和降低了术后并发症的发生,值得临床推广使用。
Objective To explore the safety and clinical efficacy of prostatic arterial embolization(PAE)in the treatment of benign prostatic hyperplasia.Methods A total of 70 patients with benign prostatic hyperplasia were randomly divided into the control group(n=35)and the treatment group(n=35).Patients with benign prostatic hyperplasia treated with PAE were selected as the treatment group,while benign prostatic hyperplasia patients treated with the transurethral plasmakinetic resection of prostate were selected as the control group.The difference of clinical efficacy and rehabilitation degree between the two groups were analyzed,including the operative time,intraoperative bleeding volume,postoperative indwelling catheter time,and postoperative hospitalization time.The complications were recorded.Moreover,the maximum urine flow rate(Qmax),residual urine volume(RUV),quality of life(QOL),international prostate symptom score(IPSS),prostatic volume(PV),hemodynamic indexes,and the levels of serum inflammatory indexes were compared between the two groups before and after treatment.Results The total effective rate of clinical treatment in the treatment group was higher than in the control group(91.43%versus 85.71%).The operative time,intraoperative bleeding volume,postoperative indwelling catheter time,postoperative hospitalization time,and complications in the treatment group were significantly lower than those in the control group,and the differences were statistically significant(all P<0.001).After 3 months of treatment,the values of Qmax,RUV,QOL,IPSS,and PV in the treatment group were better than those in the control group(all P<0.01).Moreover,the hemodynamics and inflammatory index in treatment group was better than that of the control group(P<0.05,P<0.01).Conclusion PAE has a significant effect on benign prostatic hyperplasia patients,that significantly improvs the prostate function of patients with benign prostatic hyperplasia and reduces the incidence of postoperative complications,which is worthy of clinical application.
作者
楼文杰
何帅
斯艳阳
韦家辉
LOU Wenjie;HE Shuai;SI Yanyang;WEI Jiahui(Department of Interventional,Dongyang People’s Hospital,Dongyang 310023,China;Department of Urology Surgery,Dongyang People’s Hospital,Dongyang 310023,China)
出处
《医学影像学杂志》
2023年第7期1231-1235,共5页
Journal of Medical Imaging
关键词
前列腺增生
动脉栓塞术
介入性
放射学
临床疗效
Prostatic hyperplasia
Arterial embolization
Interventional Radiology
Clinical treatment effect
