摘要
目的:观察负压滴灌联合银黄洗剂治疗糖尿病足感染的疗效及对血清相关因子的影响。方法:选取黑龙江中医药大学附属第一医院周围血管病科2020年9月—2022年9月收治的56例糖尿病足感染患者,随机分为两组,各28例。对照组给予负压滴灌联合生理盐水治疗,治疗组给予负压滴灌联合银黄洗剂治疗,疗程均为28 d。比较两组患者治疗前后创面的面积及状态(红肿、深度、肉芽形态及疼痛)评分、血清相关因子(降钙素原及C反应蛋白值)、细菌培养阳性率及总有效率。结果:治疗后,两组创面面积均较治疗前显著缩小,创面状态评分、降钙素原、C反应蛋白水平及细菌培养阳性率较治疗前显著降低,且治疗组显著低于对照组,差异有统计学意义(P<0.05)。治疗组治疗的总有效率明显高于对照组(89.29%vs 64.29%),差异有统计学意义(P<0.05)。结论:负压滴灌联合银黄洗剂治疗糖尿病足感染可有效减轻糖尿病足感染,改善创面状态,促进创面愈合。
Objective To observe the effect of negative pressure drip irrigation combined with Yinhuang lotion on diabetic foot infection and serum related factors.Methods 56 patients with diabetic foot infection were randomly divided into two groups with 28 cases in each group.The control group was treated with negative pressure drip irrigation combined with normal saline,and the treatment group was treated with negative pressure drip irrigation combined with Yinhuang lotion for 28 days.Wound area and status(redness,depth,granulation morphology and pain)scores,serum related factors(procalcitonin and C-reactive protein value),positive rate of bacterial culture and total effective rate were compared between the two groups before and after treatment.Results After treatment,the wound area in both groups significantly reduced compared with those before treatment.The wound status score,serum related factor levels and positive rate of bacterial culture significantly decreased compared with those before treatment,and the treatment group was significantly lower than that of the control group,with statistical significance(P<0.05).The total effective rate of the treatment group was significantly higher than that of the control group(89.29%vs 64.29%),with statistical significance(P<0.05).Conclusion Negative pressure drip irrigation combined with silver lotion in the treatment of diabetic foot infection can effectively reduce diabetic foot infection,improve the condition of the wound and promote wound healing.
作者
周念
贾振
梁学威
赵钢
ZHOU Nian;JIA Zhen;LIANG Xue-wei(Heilongjiang University of Traditional Chinese Medicine,Harbin(150040),China;不详)
出处
《中国中西医结合外科杂志》
CAS
2023年第4期457-462,共6页
Chinese Journal of Surgery of Integrated Traditional and Western Medicine
基金
黑龙江省中医药科研项目(ZHY2022-159)。
关键词
负压滴灌
银黄洗剂
糖尿病足感染
临床疗效
Negative pressure drip irrigation
Yinhuang lotion
diabetic foot infection
clinical effect
