摘要
目的:分析超声检查在长期服用抗精神分裂药物患者中的应用效果。方法:选取2021年1月—2022年1月铜山区济复医院收治的精神分裂症患者240例为观察对象。其中130例患者长期服用抗精神分裂药物,110例患者短期服用,分别纳入长期组、短期组。比较两组患者肝胆超声检查结果,统计不同年龄患者的肝胆超声异常率。结果:长期组脂肪肝发生率高于短期组,差异有统计学意义(P=0.001);≥55岁组脂肪肝发生率及肝胆超声异常率高于<55岁组,差异有统计学意义(P<0.001)。结论:超声检查可见,长期服用抗精神分裂药物患者发生肝脏损伤的风险较高,且随着用药时间延长、年龄增长,损伤程度越高。
Objective:To analyze the effect of ultrasonography in patients taking anti-schizophrenic drugs for a long time.Methods:240 schizophrenic patients treated in Jifu Hospital of Tongshan District from January 2021 to January 2022 were selected as the observation objects.Among them,130 patients took anti-schizophrenia drugs for a long time and 110 patients took short-term drugs,which were included in the long-term group and the short-term group respectively.The results of hepatobiliary ultrasound were compared between the two groups,and the abnormal rates of hepatobiliary ultrasound in patients of different ages were calculated.Results:The incidence of fatty liver in the long-term group was higher than that in the short-term group,the difference was statistically significant(P=0.001);The incidence of fatty liver and abnormal liver ultrasound in≥55 years old group were higher than those in<55 years old group,the difference was statistically significant(P<0.001).Conclusion:Ultrasonography showed that patients taking antipsychotic drugs for a long time had a higher risk of liver injury,and the degree of injury increased with the extension of medication time and the increase of age.
作者
刘淑红
Liu Shuhong(Department of Ultrasound,Jifu Hospital,Tongshan District,Xuzhou 221006,Jiangsu Province,China)
出处
《中外医药研究》
2023年第8期148-150,共3页
JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH
