摘要
目的调查老年脑小血管病(cerebral small vessel disease,CSVD)患者的衰弱现状并分析影响因素。方法采用便利抽样法,选取2019年1月至2020年12月于济宁医学院附属医院住院的150例老年CSVD患者,采用Fried衰弱表评估衰弱发生率。另收集研究对象的一般资料及临床相关指标,采用单因素和多因素分析老年CSVD患者衰弱的影响因素。结果衰弱患者69例,占总人数的46%;单因素分析显示,老年CSVD衰弱患者与非衰弱患者在年龄、睡眠时间、吸烟、饮酒、失能、认知障碍、营养不良、多病共存方面,差异有统计学意义(P<0.05)。多因素logistic回归分析显示,年龄、失能、认知障碍及多病共存是老年CSVD衰弱的影响因素。结论年龄、失能、认知障碍及多病共存是老年CSVD患者衰弱的影响因素。应尽早评估及衰弱管理,提高患者的生存质量。
Objective To investigate the debilitating status of elderly patients with cerebral small vessel disease and analyze the influencing factors.Methods Convenient sampling method was used to select 150 elderly patients with cerebral small vessel disease hospitalized in the Affiliated Hospital of Jining Medical University from January 2019 to December 2020.The incidence of debilitation was investigated by Fried debilitating phenotype assessment method.In addition,the general data and clinical indicators of the research subjects were collected,and single factors and multifactors were used to analyze the influencing factors of degeneration in elderly patients with cerebral small vessel disease.Results In this study,69 debilitated patients accounted for 46%of the total number;single factor analysis showed that the differences of the age,sleep time,smoking,alcohol consumption,disability,cognitive impairment and coexistence of multiple diseases in the debilitated and non-debilitated groups were statistically significant(P<0.05).The results of multivariate logistic regression analysis showed that age,disability,cognitive impairment and coexistence of multiple diseases are the influencing factors of degeneration in elderly patients with cerebral small vessel disease(P<0.05).Conclusion Age,disability,cognitive impairment and coexistence of multiple diseases are the influencing factors of degeneration in elderly patients with cerebral small vessel disease.It is recommended that elderly patients with cerebral small vessel disease undergo a comprehensive evaluation as soon as possible,and conduct various aspects of debilitating management in a timely manner to improve the quality of life of patients.
作者
王艳玲
孙洪茹
申雪花
朱雪娟
WANG Yanling;SUN Hongru;SHEN Xuehua;ZHU Xuejuan(Department of Neurology,Affiliated Hospital of Jining Medical University,Jining 272029,China)
出处
《济宁医学院学报》
2023年第4期249-252,共4页
Journal of Jining Medical University
关键词
脑小血管病
老年人
衰弱
影响因素
Cerebral smallvessel disease
Elderly
Frailty
Influencing factors