摘要
目的探讨达格列净联合降糖舒治疗老年2型糖尿病(T2DM)患者的临床效果。方法89例老年T2DM患者随机分为两组,对照组采用达格列净治疗,观察组采用达格列净联合降糖舒治疗,比较两组的临床疗效、血糖(FPG、2hPG)及胰岛功能指标(HOMA-β、HOMA-IS、HOMA-IR)。结果治疗3个月后,观察组的总有效率以及HOMA-IS、HOMA-β水平高于对照组,FPG、2hPG、HOMA-IR水平均低于对照组(P<0.05)。结论达格列净联合降糖舒治疗老年T2DM患者的临床效果显著,可明显下调患者血糖水平,改善患者胰岛功能。
Objective To explore the clinical effect of dapagliflozin combined with Jiangtangshu in the treatment of elderly patients with type 2 diabetes mellitus(T2DM).Methods 89 cases of elderly patients with T2DM were randomly divided into two groups.The control group was treated with dapagliflozin,and the observation group was treated with dapagliflozin combined with Jiangtangshu.The clinical efficacy,blood glucose(FPG,2hPG)and islet function indicators(HOMA-β,HOMA-IS,HOMA-IR)were compared between the two groups.Results After 3 months of treatment,the total effective rate and the levels of HOMA-IS and HOMA-βin the observation group were higher than those in the control group,and the levels of FPG,2hPG and HOMA-IR were lower than those in the control group(P<0.05).Conclusions Dapagliflozin combined with Jiangtangshu in the treatment of elderly patients with T2DM has significant clinical effect,which can obviously reduce the blood glucose level and improve the islet function of patients.
作者
陈晓兰
郑先雷
CHEN Xiaolan;ZHENG Xianlei(Department of Endocrinology,Xinyang People's Hospital,Xinyang 464000,China)
出处
《临床医学工程》
2023年第8期1079-1080,共2页
Clinical Medicine & Engineering
关键词
达格列净
降糖舒
老年
2型糖尿病
血糖水平
胰岛功能
Dapagliflozin
Jiangtangshu
Elderly
Type 2 diabetes mellitus
Blood glucose level
Islet function
