摘要
目的对不同孕周妇女甲状腺功能三项检测结果及其临床意义加以探讨和分析。方法选取我院2020年2月至2022年2月期间接收的不同孕周妇女共300例进行研究,其中孕早期组、孕中期组和孕晚期组的例数均为100例,并选取同时期在我院健康体检的未怀孕女性100例作为对照组,四组受试者均行甲状腺功能三项检测,对比四组检测结果,分析孕周与甲状腺功能三项水平间的关系以及临床指导价值。结果对照组和不同孕期的孕妇的TSH、FT3、FT4指标有较为显著差异,体现的规律为孕周越长,则TSH指标升高越明显,而FT3、FT4下降则越明显。根据Spearman秩相关系数分析孕周和甲状腺三项指标之间的关系发现,二者具有密切相关性,孕周和TSH、FT3、FT4的相关性分别表示为正相关性、负相关性、负相关性。分析300例孕妇的妊娠结局发现其中有120例孕妇发生的不良结局,有180例孕妇妊娠结局良好。分析孕妇的一般资料发现不同妊娠结局孕肚的体质指数、孕次无统计学差异(P>0.05);而不同妊娠结局孕妇存在统计学差异的指标包括孕周、产次、年龄、甲状腺功能三项异常(P<0.05)。运用多元线性回归线对多种因素进行分析发现妊娠结局和甲状腺功能三项之间关系密切(P<0.05)。结论检测不同孕周的孕妇甲状腺功能三项检测结果发现和孕周存在着明显的相关性,且影响着妊娠结局,积极监测孕期的各项指标水平变化情况并制定出相应的治疗方案对改善孕妇和围生儿身体健康意义显著。
Objective To explore and analyze the results of three tests of thyroid function in women with different gestational weeks and their clinical significance.Methods A total of 300 women of different gestational weeks admitted to our hospital from February 2020 to February 2022 were selected for the study,including 100 cases in the first trimester group,second trimester group and third trimester group,and 100 cases of nonpregnant women who had physical examination in our hospital during the same period were selected as the control group.All subjects in the four groups underwent three tests of thyroid function.The results of the four groups were compared,and the relationship between gestational age and thyroid function levels was analyzed as well as the clinical guidance value.Results There were significant differences in TSH,FT3 and FT4 indexes between the control group and the pregnant women in different pregnancies.The rule reflected was that the longer the gestational age,the more obvious the increase of TSH indexes was,while the more obvious the decrease of FT3 and FT4 was.Spearman rank correlation coefficient was used to analyze the relationship between gestational age and thyroid indicators.It was found that they were closely correlated,and the correlation between gestational age and TSH,FT3 and FT4 was expressed as positive correlation,negative correlation and negative correlation,respectively.Analysis of the pregnancy outcomes of 300 pregnant women found that 120 pregnant women had adverse outcomes and 180 pregnant women had good outcomes.By analyzing the general data of pregnant women,there were no significant differences in body mass index(BMI)and gestational number among different pregnancy outcomes(P>0.05).There were significant differences in gestational age,parity,age and thyroid function among pregnant women with different pregnancy outcomes(P<0.05).Multivariate linear regression analysis showed that there was a close relationship between pregnancy outcome and thyroid function(P<0.05).Conclusion The results of three tests of thyroid function of pregnant women at different gestational ages were found to be significantly correlated with gestational age,and affected the pregnancy outcome.It is of great significance to actively monitor the changes of various indicators during pregnancy and develop corresponding treatment plans to improve the physical health of pregnant women and perinatal infants.
作者
苌哲宗
杜帅格
Chang Zhe-zong;Du Shuai-ge(Pingmei Shenma Medical Group General Hospital,Pingdingshan 467000,Henan Province,China)
出处
《罕少疾病杂志》
2023年第8期98-99,102,共3页
Journal of Rare and Uncommon Diseases
关键词
不同孕周
妇女
甲状腺功能
三项检测
临床意义
Different Gestational Age
Women
Thyroid Function
Three Tests
Clinical Significance
