摘要
甲状腺癌(THCA)是一种常见的头颈部恶性肿瘤,近年来发病率逐年上升。而THCA的危险因素不明确,相关研究表明这可能与人口特征因素、环境因素、遗传与表观遗传因素等有关,其中表观遗传因素是近年来THCA发病机制方面研究的热点。该文就表观遗传中的RNA甲基化因素进行综述,为进一步揭示THCA的发病机制、了解其预后及遗传性等,为THCA的精准和科学防控提供依据。
Thyroid cancer(THCA)is a common malignant tumor of the head and neck,and the incidence rate has increased year by year in recent years.The risk factors of THCA are not clear,and relevant studies have shown that this may be related to demographic factors,environmental factors,genetic and epigenetic factors,among which epigenetic factors are the research hotspots in the pathogenesis of THCA in recent years.In this paper,RNA methylation factors in epigenetics were reviewed,in order to further reveal the pathogenesis of THCA,understand its prognosis and hereditability,and provide a basis for the accurate and scientific prevention and control of THCA.
作者
温思妮
刘瀚元
韩菲
田润
徐圣奉
朱小年
谭盛葵(综述)
张慧霞(审校)
WEN Sini;LIU Hanyuan;HAN Fei;TIAN Run;XU Shengfeng;ZHU Xiaonian;TAN Shengkui;ZHANG Huixia(School of Public Health,Guilin Medical College,Guilin,Guangxi 541000,China;Guangxi Key Laboratory of Environmental Exposure and Full Life Cycle Health Technology,Guilin,Guangxi 541000,China;West China School of Public Health,Sichuan University,Chengdu,Sichuan 610000,China)
出处
《现代医药卫生》
2023年第16期2799-2804,2811,共7页
Journal of Modern Medicine & Health
基金
教育部大学生创新创业训练计划项目(S202110601110)
桂林医学院硕士研究生科研项目(GYYK2021005)
联合培养基地研究生教育创新计划项目-桂林医学院硕士研究生科研项目(GWXY202002,GWXY202010)。
