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电针俞募配穴联合高强度间歇性运动对单纯性肥胖患者内脏脂肪及糖脂代谢的影响 被引量:4

Effects of electroacupuncture at both back-Shu and front-Mu points combined with high-intensity interval training on visceral adipose and glucolipid metabolism in patients with simple obesity
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摘要 目的观察电针俞募配穴联合高强度间歇性运动对单纯性肥胖患者人体学参数、内脏脂肪指数、脂质蓄积指数及糖脂代谢指标的影响。方法将100例单纯性肥胖患者随机分为观察组(46例,脱落4例)和对照组(45例,脱落5例)。对照组采用电针俞募配穴,观察组选用电针俞募配穴+高强度间歇性训练,两组患者隔日治疗1次,每周3次,疗程均为12周,并同以饮食控制为基础干预。比较两组治疗前后的人体学参数指标[体质量(body weight,BW)、体质量指数(body mass index,BMI)、腰围(waist circumference,WC)]、内脏脂肪指数(visceral adiposity index,VAI)、脂质蓄积指数(lipid accumulation product,LAP)、血脂成分[总胆固醇(total cholesterol,TC)、三酰甘油(triacylglycerol,TG)、高密度脂蛋白胆固醇(high-density lipoprotein cholesterol,HDL-C)、低密度脂蛋白胆固醇(low-density lipoprotein cholesterol,LDL-C)]及糖代谢[空腹血糖(fasting blood glucose,FBG)、空腹胰岛素(fasting insulin,FINS)、胰岛素抵抗指数(insulin resistance,HOMA-IR)]等变化情况。结果(1)两组治疗后BW、BMI、WC较治疗前均降低(P<0.01)。(2)观察组治疗后TC、LDL-C、TG较治疗前降低(P<0.05,P<0.01),HDL-C较治疗前升高(P<0.01);对照组治疗后TC、LDL-C较治疗前降低(P<0.05,P<0.01),TG、HDL-C较治疗前差异无统计学意义(P>0.05)。(3)观察组治疗后LAP、VAI较治疗前均降低(P<0.01);对照组治疗后LAP较治疗前降低(P<0.05),而VAI无明显变化(P>0.05);观察组LAP、VAI治疗前后差值大于对照组(P<0.01)。(4)观察组治疗后FBG、FINS、HOMA-IR均较治疗前降低(P<0.01);对照组治疗后FIN、HOMA-IR较治疗前降低(P<0.05),FBG较治疗前差异无统计学意义(P>0.05);观察组治疗后FBG较对照组低(P<0.05),FBG、HOMA-IR治疗前后差值大于对照组(P<0.05)。结论两组方法对单纯性肥胖均有一定疗效,电针俞募配穴联合高强度间歇性训练在改善单纯性肥胖患者内脏脂肪指数、脂质蓄积指数及糖脂代谢方面优于单纯电针俞募配穴。 Objective To observe the effects of electroacupuncture(EA)at both back-Shu and front-Mu points combined with high-intensity interval training(HIIT)on somatological parameters,visceral adiposity index(VAI),lipid accumulation product(LAP),and glucolipid metabolism in patients with simple obesity.Methods A total of 100 patients with simple obesity were randomized into observation group(46 cases,4 cases dropped off)and control group(45 cases,5 cases dropped off).The control group was treated with EA at both back-Shu and front-Mu points,while the observation group was treated with EA at both back-Shu and front-Mu points combined with HIIT.Both groups were treated once every other day,three times a week,for a total of 12 weeks,and the interventions were based on diet control.The changes of somatological parameters[body weight(BW),body mass index(BMI),and waist circumference(WC)],VAI,LAP,blood lipid components[total cholesterol(TC),triglyceride(TG),high-density lipoprotein cholesterol(HDL-C),and low density lipoprotein cholesterol(LDL-C)],and glucose metabolism[fasting blood glucose(FBG),fasting insulin(FINS),and insulin resistance index(HOMA-IR)]were compared between the two groups before and after treatment.Results(1)After treatment,BW,BMI,and WC in both groups were lower than those before treatment(P<0.01).(2)After treatment,TC,LDL-C,and TG in the observation group were lower than those before treatment(P<0.05,P<0.01),while HDL-C was higher than that before treatment(P<0.01);TC and LDL-C in the control group were lower than those before treatment(P<0.05,P<0.01),and there was no significant difference in TG and HDL-C between before and after treatment(P>0.05).(3)After treatment,LAP and VAI in the observation group were lower than those before treatment(P<0.01);LAP in the control group was lower than that before treatment(P<0.01),but there was no significant difference in VAI between before and after treatment(P>0.05);the difference values of LAP and VAI between before and after treatment in the observation group were greater than those in the control group(P<0.01).(4)After treatment,FBG,FINS,and HOMA-IR in the observation group were lower than those before treatment(P<0.01);FINS and HOMA-IR in the control group were lower than those before treatment(P<0.01),and there was no significant difference in FBG between before and after treatment(P>0.05).Moreover,FBG of the observation group was lower than that of the control group(P<0.05),and the difference values of FBG and HOMA-IR between before and after treatment in the observation group were greater than those in the control group(P<0.05).Conclusion Both methods show positive effects on simple obesity.Furthermore,EA at both back-Shu and front-Mu points combined with HIIT is superior to EA at both back-Shu and front-Mu points alone in improving VAI,LAP,and glucolipid metabolism in patients with simple obesity.
作者 王平 钟润琪 岳增辉 WANG Ping;ZHONG Runqi;YUE Zenghui(Hunan University of Chinese Medicine,Changsha,Hunan 410208,China;Xiangya Hospital of Central South University,Changsha,Hunan 410079,China)
出处 《湖南中医药大学学报》 CAS 2023年第8期1492-1497,共6页 Journal of Hunan University of Chinese Medicine
基金 湖南省临床医疗技术创新引导项目(2017SK50114)。
关键词 电针 俞募配穴 高强度间歇性运动 单纯性肥胖 内脏脂肪 糖脂代谢 electroacupuncture back-Shu and front-Mu point combination high-intensity interval training simple obesity visceral adipose glucolipid metabolism
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