摘要
目的分析急性脑梗死静脉溶栓治疗后出血转化的危险因素。方法抽取2021年3月至2022年6月河南省人民医院收治的108例急性脑梗死患者作为研究对象,所有患者均接受静脉溶栓治疗,将其中31例静脉溶栓后出现出血转化的患者纳入研究组,77例未出现出血转化的患者纳入对照组。分析两组患者各项指标,通过多因素Logistic回归分析总结急性脑梗死后出血转化的影响因素。结果研究组心房纤颤病史者占比、空腹血糖高者占比、糖尿病病史者占比、大面积急性脑梗死者占比均高于对照组,差异有统计学意义(P<0.05)。多因素Logistic回归分析结果显示,血糖指标高、心房纤颤病史、大面积急性脑梗死均为急性脑梗死静脉溶栓治疗后出血转化的危险因素(P均<0.05)。结论空腹血糖水平高、心房纤颤史、大面积急性脑梗死是急性脑梗死静脉溶栓治疗后出血转化的独立危险因素。
Objective To analyze the risk factors of hemorrhagic transformation after intravenous thrombolysis in patients with acute cerebral infarction.Methods One hundred and eight patients with acute cerebral infarction treated in Henan Provincial People’s Hospital from March 2021 to June 2022 were selected as the study subjects.All patients received intravenous thrombolysis;among them,31 patients with hemorrhagic transformation after intravenous thrombolysis were enrolled in the study group,while 77 patients without hemorrhagic transformation were included in the control group.The various indicators of the two groups were analyzed,and the influencing factors of hemorrhagic transformation after acute cerebral infarction were summarized through multivariate logistic regression analysis.Results The proportion of patients with history of atrial fibrillation,high fasting blood glucose,diabetes history and large-area acute cerebral infarction in the study group were higher than those in the control group,and the difference was statistically significant(P<0.05).The results of multivariate logistic regression analysis showed that high blood glucose level,history of atrial fibrillation,large-area acute infarction were all the risk factors for hemorrhagic transformation after acute cerebral infarction(all P<0.05).Conclusions High fasting blood glucose level,history of atrial fibrillation and large-area acute cerebral infarction are independent risk factors of hemorrhagic transformation after intravenous thrombolysis in patients with acute cerebral infarction.
作者
李伟丽
王丹
马明明
Li Weili;Wang Dan;Ma Mingming(Department of Neurology,Henan Provincial People’s Hospital,Henan Provincial Cerebrovascular Disease Hospital,People’s Hospital of Zhengzhou University,Henan Key Laboratory of Nursing Medicine,Zhengzhou 450000,China)
出处
《中国实用医刊》
2023年第10期14-17,共4页
Chinese Journal of Practical Medicine
关键词
脑梗死
出血转化
影响因素
Cerebral infarction
Hemorrhagic transformation
Influencing factors
