摘要
咽喉反流(LPR)是指胃内容物反流到喉部和咽部,临床上表现为异物感、发音困难和吞咽困难等各种咽喉症状。传统的LPR诊断方法基于临床病史和喉镜检查,包括假声带沟、慢性咽喉炎、后联合肥大和黏膜分泌物增厚等表现。由于LPR在发病机制上与胃食管反流病(GERD)相关,且在接受GERD相关治疗后,LPR症状会得到一定缓解,部分学者将LPR归为GERD的食管外症状。尽管目前存在将两者区分开的主流观点,但一些GERD的诊疗方法也可用于LPR的诊断和治疗。本文综述近年来与LPR和GERD相关的诊断和治疗进展,并提出合理的诊疗流程,旨在为未来诊断和治疗LPR提供参考。
Laryngopharyngeal reflux(LPR)refers to the backflow of stomach contents into the throat and pharynx,clinically presenting with various throat symptoms such as a sensation of foreign body,difficulty in pronunciation and swallowing.Traditional methods for diagnosing LPRare based on clinical history and laryngoscopic examination,which include findings such as vocal cord groove,chronic pharyngolaryngitis,posterior laryngitis,and increased mucosal secretions.As LPRis closely related to gastroesophageal reflux disease(GERD)in terms of pathogenesis,and LPRsymptoms can be relieved to some extent after receiving GERD-related treatment,some scholars also classify LPRas an extra-esophageal symptom of GERD.Although there is currently a mainstream view of distinguishing the two diseases,some diagnostic and therapeutic methods for GERD can also be used for the diagnosis and treatment of LPR.This paper aimed to review the recent advances in the diagnosis and treatment of LPRand GERD,and propose a rational diagnostic and therapeutic process as a reference for diagnosis and treatment of LPRin the future.
作者
董泓毅
刘殿刚
DONG Hongyi;LIU Diangang(Department of General Surgery,Xuanwu Hospital of Capital Medical University,Beijing,100053)
出处
《实用临床医药杂志》
2023年第14期109-114,共6页
Journal of Clinical Medicine in Practice
基金
北京市自然科学基金资助项目(L182048)。
关键词
咽喉反流
胃食管反流
吞咽困难
慢性咽喉炎
抗反流手术
laryngopharyngeal reflux
gastroesophageal reflux
difficulty in swallowing
chronic pharyngitis
anti-reflux surgery