摘要
目的比较西安大略和麦克马斯特大学骨关节炎指数(WOMAC)量表、医疗结果研究36项简表(SF-36量表)与《大骨节病治疗效果判定》(WS/T 79-2011)标准在大骨节病患者疗效评价中的应用效果,为大骨节病患者治疗评价提供依据。方法以甘肃省213名大骨节病患者为调查对象,分别采用WOMAC、SF-36量表与WS/T 79-2011标准分析大骨节病患者治疗前后生活质量。比较WOMAC、SF-36量表的信度、结构效度、内容效度、区分效度,并分析WOMAC、SF-36量表与WS/T 79-2011标准之间的相关性。结果WOMAC、SF-36量表均具有较好的结构效度与内容效度(结构效度:WOMAC、SF-36量表分别含1、2个公因子;内容效度:WOMAC、SF-36量表分别含3、8个公因子);WOMAC量表的信度、区分效度均优于SF-36量表(信度:WOMAC量表信度系数均≥0.934,而SF-36量表信度系数范围为0.386~0.999;区分效度:患者治疗前后WOMAC量表3个领域均有差异,而SF-36量表8个领域中6个领域有差异)。WOMAC、SF-36量表与WS/T 79-2011标准不同领域间相关系数(r)分别为0.175~0.437、-0.434~-0.099(均P<0.05)。结论WOMAC量表在大骨节病患者疗效评价中信度、区分效度、与WS/T 79-2011标准的相关性均优于SF-36量表。
Objective To compare the application effect among Western Ontario and McMaster University Osteoarthritis Index(WOMAC)scale,Medical Outcomes Study 36-item Short Form(SF-36)scale and"Assessment for Therapeutic Efficacy on Kashin-Beck Disease"(WS/T 79-2011)standard in the evaluation of therapeutic effect of patients with Kashin-Beck disease,which could provide basis for the treatment evaluation of patients with Kashin-Beck disease.Methods A total of 213 patients with Kashin-Beck disease in Gansu Province were investigated.WOMAC scale,SF-36 scale and standard of WS/T 79-2011 were used to analyze the quality of life of patients before and after treatment.The reliability,construct validity,content validity,discriminant validity of WOMAC and SF-36 scales were compared.Correlation between WOMAC,SF-36 scales and standard of WS/T 79-2011 were evaluated.Results Both WOMAC and SF-36 scales had good construct validity and content validity(construct validity showed WOMAC and SF-36 scales contained 1 and 2 common factors,respectively;content validity showed WOMAC and SF-36 scales contained 3 and 8 common factors,respectively).The reliability and discriminant validity of WOMAC scale were better than those of SF-36 seale(reliability showed WOMAC reliability coefficient≥0.934,the reliability coefficient of SF-36 scale was ranged from 0.386 to 0.999.Discriminant validity showed there were differences in 3 dimensions of the WOMAC scale before and after treatment,while there were differences in 6 out of 8 dimensions of the SF-36 scale).The correlation coefficients between WOMAC scale and standard of WS/T 79-2011 ranged from 0.175 to 0.437,the correlation coefficients between SF-36 scale and standard of WS/T 79-2011 ranged from-0.434 to-0.099(P<0.05).Conclusion The reliability,discriminant validity and correlation with the standard of WS/T 79-2011 of WOMAC scale are better than those of SF-36 scale in efficacy evaluation of patients with Kashin-Beck disease.
作者
费秀兰
陈晓燕
王燕玲
陈国华
李萍
鱼素琴
柏淑英
Fei Xiulan;Chen Xiaoyan;Wang Yanling;Chen Guohua;Li Ping;Yu Suqin;Bai Shuying(Department of Endemic Disease,Gansu Center for Disease Prevention and Control,Lanzhou 730020,China)
出处
《中华地方病学杂志》
CAS
北大核心
2023年第8期618-622,共5页
Chinese Journal of Endemiology
基金
甘肃省科技计划项目(22JR5RA714)
兰州市人才创新创业项目(2021-RC-110)
甘肃省中医药管理局科研课题(GZK-2019-57)。
