摘要
肠道菌群对维持机体免疫平衡、消化和营养吸收起着重要作用。甲状腺功能主要包括甲状腺激素合成、分泌以及调节体内代谢平衡,当机体甲状腺激素合成和分泌过少或过多时,则会导致甲状腺类疾病发生。现已有研究表明肠道菌群可能通过参与甲状腺代谢、免疫调节、交叉免疫反应及与甲状腺相关的易感因素相互作用而影响甲状腺疾病的发生发展。了解甲状腺疾病发生发展过程中肠道菌群的结构变化和功能机制,可为甲状腺疾病的诊断、治疗和改善临床预后提供新依据。
Intestinal flora plays an important role in maintaining the body′s immune balance,digestion,and nutrient absorption.Thyroid function mainly includes the synthesis and secretion of thyroid hormones and the regulation of metabolic balance in the body.When the body′s thyroid hormone synthesis and secretion are too little or too much,it will lead to thyroid diseases.Studies have shown that intestinal flora may affect the occurrence and development of thyroid diseases by participating in thyroid metabolism,immune regulation,cross immunoreaction,and interaction with thyroid-related predisposing factors.Understanding the structural changes and functional mechanisms of intestinal flora during the occurrence and development of thyroid diseases can provide a new basis for the diagnosis and treatment of thyroid diseases and improvement of clinical prognosis.
作者
张玮
罗茹心
蒲岚
ZHANG Wei;LUO Ruxin;PU Lan(West China School of Nursing,Sichuan University/Department of Nuclear Medicine,West China Hospital,Sichuan University,Chengdu,Sichuan 610041,China)
出处
《公共卫生与预防医学》
2023年第5期116-119,共4页
Journal of Public Health and Preventive Medicine
基金
四川大学华西护理学科发展专项基金项目(HXHL21043)。
关键词
肠道菌群
甲状腺
免疫调节
交叉免疫
易感因素
Intestinal flora
Thyroid gland
Immune regulation
Cross immunization
Predisposing factors
