摘要
目的探究新损伤严重度评分(new injury severity score,NISS)联合乳酸(lactic,Lac)及甘油三酯葡萄糖指数(triglyceride glucose index,TyG)对非糖尿病多发伤患者72h病死率的预测价值。方法回顾性分析2019年11月—2021年11月安徽医科大学第二附属医院急诊外科收治非糖尿病多发伤患者资料147例,收集患者一般资料、NISS和入院24h内初始Lac、甘油三脂、空腹血糖,并计算TyG值,按照入院72h救治结果不同分为存活组(94例)和死亡组(53例)。应用SPSS26.0统计软件对各指标进行组间比较,采用受试者工作(receiver operating characteristic,ROC)曲线预测上述指标在评估病情严重程度中的灵敏度与特异度。结果147例患者72h内死亡53例,病死率36.1%(95%CI0.28~0.45),两组患者性别、年龄、体质量指数组间比较差异无统计学意义(P>0.05),存活组与死亡组患者NISS、Lac、TyG三者比较差异有统计学意义(P<0.05)。ROC示NISS、Lac、TyG及联合检测的ROC曲线下面积分别为0.705、0.684、0.720和0.834。结论NISS、Lac及TyG三者联合较单用三项指标对非糖尿病多发伤患者72h病死率预测价值较高,具有一定的临床应用价值。
Objective To investigate the predictive value of new injury severity score(NISS)combined with lactate(Lac)and triglyceride glucose index(TyG)for 72-h mortality in patients with non-diabetic multiple injuries.Methods A retrospective study was conducted on clinical data of 147 patients with non-diabetes multiple injuries admitted to the emergency department of the Second Hospital of Anhui Medical University from Nov.2019 to Nov.2021.Information collected included general data,NISS,and initial levels of lactate,triglyceride and fasting blood glucose within 24 h of admission.TyG value was then calculated.Based on the 72-h treatment outcome after admission,patients were divided into survival group(n=94)and non-survival group(n=53).SPSS 26.0 statistical software was adopted for data analysis and the receiver operating characteristic(ROC)curve to predict the sensitivity and specificity of the abovementioned indicators in assessing the disease severity.Results Within 72 h after admission,53 cases died,with the mortality rate being 36.1%(95%CI=0.28-0.45).Comparison of the survivors and non-survivors revealed no significant difference in gender,age,and body mass index(all P>0.05),but significant difference in NISS,Lac and TyG(all P<0.05).It was shown that the area under the ROC curve for separate NISS,Lac,TyG,and combined detection of the three parameters was 0.705,0.684,0.720 and 0.834,respectively.Conclusion Compared with their use alone,the combination of NISS,Lac and TyG presents a higher predictive value for the 72-h mortality in non-diabetic patients with multiple trauma,and has certain application value in clinic.
作者
金太阳
徐炎松
孙远松
尹纯林
王召华
李贺
Jin Taiyang;Xu Yansong;Sun Yuansong;Yin Chunlin;Wang Zhaohua;Li He(Emergency Department,the Second Hospital of Anhui Medical University,Hefei 230000,China)
出处
《创伤外科杂志》
2023年第9期696-701,共6页
Journal of Traumatic Surgery
基金
中国初级卫生保健基金会(YLGX-JZ-2020002)
2021年高校优秀青年人才项目(gxyq2021170)。
