摘要
目的 了解复旦大学附属中山医院厦门医院住院药房第二类精神药品的使用概况,为临床用药提供参考。方法 对复旦大学附属中山医院厦门医院2020—2022年住院药房使用的第二类精神药物的销售额进行统计,并对其使用频率(DDDs)、日均费用(DDC)和排序比例[按销售额排序(B)/DDDs排序(A)]统计分析,评价其使用的合理性。结果 2020—2022年,复旦大学附属中山医院厦门医院住院药房的第二类精神药品销售总金额占全院药品的比例均逐年加大;地佐辛注射液、咪达唑仑注射液及苯磺酸瑞马唑仑销售金额居上,唑吡坦片的DDDs值稳居排列首位,艾司唑仑的DDDs值稳居第四。艾司唑仑片、阿普唑仑片用量大且价格亲民;地佐辛注射液、喷他佐辛注射液、布托啡诺注射液、苯磺酸瑞马唑仑的DDC值排前四位,单价较高;唑吡坦片、阿普唑仑片、艾司唑仑的B/A均大于1.0,使用频率较高。氯硝西泮片、地西泮片的B/A接近1.0,药品同步性好。结论 复旦大学附属中山医院厦门医院第二类精神药品基本可以满足临床需求,其中唑吡坦片使用频率最高,氯硝西泮片价格同步性最佳。医院应继续加强监督管理,规范临床使用,以确保患者用药安全、合理。
Objective To investigate the use of classⅡpsychotropic drugs in the inpatient pharmacy of Zhongshan Hospital,Fudan University(Xiamen Branch),and to provide a reference for clinical medication.Methods The sales volume of the ClassⅡpsychotropic drugs used in the inpatient pharmacy of Zhongshan Hospital,Fudan University(Xiamen Branch)from 2020 to 2022 was statistically analyzed,and the defined daily doses(DDDs),defined daily cost(DDC),and the ranking ratio(by sales volume[B]/DDDs[A])were statistically analyzed to evaluate the rationality of drug use.Results From 2020 to 2022,the proportion of the total sales amount of ClassⅡpsychotropic drugs in the inpatient pharmacy of Zhongshan Hospital,Fudan University(Xiamen Branch)in the total sales amount of drugs in the entire hospital increased year by year.The sales amount of dezocine injection,midazolam injection,and remimazolam besylate ranked first,the DDDs value of zolpidem tablets ranked first,and the DDDs value of estazolam ranked fourth.Eszolam tablets and alprazolam tablets are widely used and affordable;The DDC values of dizosin injection,pentazosin injection,butorphanol injection,and remazazolam benzenesulfonate ranked in the top four,with higher unit prices;The B/A of zolpidem tablets,alprazolam tablets,and estazolam tablets are all greater than 1.0,indicating a higher frequency of use.The B/A of clonazepam tablets and diazepam tablets is close to 1.0,indicating good drug synchronization.Conclusion The ClassⅡpsychotropic drugs in Zhongshan Hospital,Fudan University(Xiamen Branch)can basically meet the clinical demands,with zolpidem tablets being used most frequently,and clonazepam tablets being the best in price synchronization.The hospital should continue to strengthen supervision and management and standardize clinical use,so as to ensure the safety and rationality of patient medication.
作者
翁丽玲
陈继涢
施婷婷
叶岩荣
WENG Liling;CHEN Jiyun;SHI Tingting;YE Yanrong(Pharmacy Department,Zhongshan Hospital,Fudan University(Xiamen Branch),Fujian,Xiamen 361000,China;Pharmacy Department,Zhongshan Hospital,Fudan University,Shanghai 200032,China)
出处
《中国医药科学》
2023年第16期126-130,共5页
China Medicine And Pharmacy
关键词
第二类精神药品
用药频度
日均费用
排序比
合理用药
ClassⅡpsychotropic drugs
Defined daily doses
Defined daily cost
Ranking ratio
Rational use
