摘要
对北京动物园2005—2016年病死野生动物病原菌分离的情况统计分析发现,在168种537只动物的935份样本中,307只动物的515份样本分离到病原菌580株,检出率为57.17%;其中,革兰氏阴性菌占62.20%,同时还发现大肠杆菌Escherichia coli、链球菌属Streptococcus、肺炎克雷伯氏菌Klebsiella pneumoniae、魏氏梭菌Clostridium welchii和铜绿假单胞菌Pseudomonas aeruginosa等。病变脏器以肝脏(31.33%)和肺脏(22.46%)最多,肺脏标本的病原菌检出率最高(62.38%),说明呼吸系统疾病在圈养野生动物疾病中的占比较高。部分菌株的药敏试验结果显示,病原菌对磺胺、青霉素的耐药性为25.00%~78.57%,而对头孢曲松、庆大霉素等的耐药性为10.00%~36.36%。本结果可以指导临床治疗用药,避免耐药菌株的产生。
In order to understand the proportion of bacterial infectious diseases and the drug resistance of pathogenic bacteria among the wild animals in Beijing Zoo,935 samples collected from 537 individuals of 168 species from 2005 to 2016 were statistically analyzed.A total of 580 bacterial isolates,including 62.20%of gram-negative(such as Escherichia coli,Streptococcus,Klebsiella pneumoniae,and Pseudomonas aeruginosa)and 37.79%of gram-positive(such as Clostridium perfringens),were identified among 307 individuals of 515 samples,with a detection rate of 57.17%.According to the analysis of the types of pathological organs,the proportions of liver and lung were 31.33%and 22.46%,respectively.The pathogenic bacterial isolates from lung samples accounted for 62.38%,suggested that respiratory infections are the main diseases of wild animals in captivity.Moreover,the bacterial pathogens were sensitive to ceftriaxone and gentamicin,but strongly resistant to sulforaphane and penicillin.The result of this study provides a reference for clinical treatment to prevent the emergence of drug-resistant strains.
作者
刘燕
詹同彤
胡昕
卢岩
郝菲儿
由玉岩
崔多英
刘赫
滑荣
张成林
LIU Yan;ZHAN Tongtong;HU Xin;LU Yan;HAO Feier;YOU Yuyan;CUI Duoying;LIU He;HUA Rong;ZHANG Chenglin(Beijing Zoo Management Office,Beijing Key Laboratory of Captive Wildlife Technology,Beijing 100044,China)
出处
《四川动物》
北大核心
2023年第5期547-551,共5页
Sichuan Journal of Zoology
基金
北京市公园管理中心项目(kjxx2021006)
北京动物园开放课题项目(ZDK202202,ZDK202206)。
关键词
圈养野生动物
病原菌分布
耐药性
captive wildlife
pathogen distribution
drug resistance
