摘要
目的分析三维动脉自旋标记(3D-ASL)联合动态对比增强磁共振成像(DCE-MRI)技术诊断脑胶质瘤术后复发与放射性脑坏死的临床价值。方法对2019年1月至2021年12月涿州市医院行术后辅助放射治疗的脑胶质瘤患者(60例)的临床资料进行回顾性研究,常规MRI检查发现新增异常强化灶,经二次手术病理检查证实后将其分为脑胶质瘤术后复发组(n=38)与放射性脑坏死组(n=22)。两组患者分别进行MRI、3D-ASL、DCE-MRI检查,获取3D-ASL和DCE-MRI的定量参数,分析应用3D-ASL联合DCE-MRI诊断脑胶质瘤术后复发与放射性脑坏死的临床价值。结果脑胶质瘤术后复发组的rCBF、Ktrans值均高于放射性脑坏死组(P<0.05)。3D-ASL联合DCE-MRI检查的准确率高于单一检查(P<0.05)。3D-ASL联合DCE-MRI检查的灵敏度、特异度、准确度、阳性预测值、阴性预测值均高于单一检查(P<0.05)。结论临床可应用3D-ASL联合DCE-MRI对脑胶质瘤术后复发与放射性脑坏死进行区分,提高诊断准确率。
Objective To analyze the clinical value of three-dimensional arterial spin labeling(3D-ASL)combined with dynamic contrast enhanced magnetic resonance imaging(DCE-MRI)in the diagnosis of recurrence of glioma and radiation brain necrosis.Methods Retrospective study was conducted on the clinical data of 60 patients with glioma who received postoperative adjuvant radiotherapy in Zhuozhou City Hospital from January 2019 to December 2021.The new abnormal enhancement lesions were found by routine MRI examination,and they were divided into postoperative recurrence group of glioma(n=38)and radiation brain necrosis group(n=22)after confirmed by secondary surgical pathology.The patients in both groups received MRI,3D-ASL and DCE-MRI to obtain the quantitative parameters of 3D-ASL and DCE-MRI.The parameters of the two groups were compared and the clinical value of 3D-ASL combined with DCE-MRI in the diagnosis of postoperative recurrence and radiation brain necrosis of glioma was analyzed.Results The rCBF and Ktrans values of glioma recurrence group were higher than those of radiation brain necrosis group(P<0.05).The accuracy of 3D-ASL combined with DCE-MRI was higher than that of single examination(P<0.05).The sensitivity,specificity,accuracy,positive predictive value and negative predictive value of 3D-ASL combined with DCE-MRI were higher than those of single examination(P<0.05).Conclusion 3D-ASL combined with DCE-MRI can be used clinically to distinguish the recurrence of brain glioma from radiation brain necrosis.The combined examination of the two has extremely high diagnostic value and can improve the diagnostic accuracy.
作者
冯海涛
徐涛
刘文阳
孙晨
曹尚超
Feng Haitao;Xu Tao;Liu Wenyang;Sun Chen;Cao Shangchao(Department of Imaging,Zhuozhou City Hospital,Zhuozhou 072750,China)
出处
《中华消化病与影像杂志（电子版）》
2023年第4期262-265,共4页
Chinese Journal of Digestion and Medical Imageology(Electronic Edition)
基金
保定市科技计划项目(2141ZF344)。
关键词
脑胶质瘤
放射性脑坏死
三维动脉自旋标记
动态对比增强磁共振成像
Glioma
Radiation brain necrosis
Three-dimensional arterial spin labeling
Dynamic contrast enhanced magnetic resonance imaging
