摘要
目的基于中医传承辅助平台(V2.5)挖掘应用扶阳法治疗眼病的制方用药规律。方法检索1982年1月—2022年9月中国知网、万方和维普数据库中关于扶阳法应用于中医眼科的相关文献。将检索结果导出至NoteExpress软件去除重复文献,排除不符合纳入标准的文献,之后将文献信息录入Excel 2010建立数据库,对中药名称、四气、五味和归经进行统一规范化处理后,采用中医传承辅助平台软件进行统计分析。结果(1)一般情况:共纳入文献81篇,涉及处方共138个,中药168味,药物总频次累计1,350次。(2)处方五脏归属:共计12类,排在前5位的分别是脾(42次,30.43%)、脾肾(28次,20.29%)、肾(24次,17.39%)、肝(16次,11.59%)、心(6次,4.35%)。(3)处方使用频次:排在前5位的分别为吴茱萸汤(11次,7.97%)、苓桂术甘汤(9次,6.52%)、补中益气汤(8次,5.80%)、肾气丸(7次,5.07%)、真武汤(6次,3.62%)。(4)中药药性:四气以温性药(47次,27.98%)最多,五味以甘味药(69次,41.07%)最多,归经以脾经(40次,23.81%)最多。(5)高频中药用药频次:排在前5位的依次为茯苓(71次,5.26%),白术(68次,5.04%),黄芪(60次,4.44%),附子(54次,4.00%),桂枝(51次,3.78%)。(6)核心药对组合:共得到14个核心药对组合。关联度性最高的5对依次为白术-茯苓、黄芪-白术、桂枝-茯苓、白术-桂枝、黄芪-茯苓。结论扶阳法治疗眼病时常选择扶助脾、肾、肝阳之方,但用药不拘泥于温热补阳药物,常配伍益气、淡渗、辛散之品以滋养、顾护、疏通阳气,从而畅通目系、助阳气布散,常用方药及配伍具有一定的中医眼科专科特色。
OBJECTIVE To explore the prescription and medication rules of reinforcing Yang for eye diseases in Ophthalmology of Traditional Chinese Medicine(TCM)based on TCM inheritance support platform(Version 2.5).METHODS Relevant literature on the application of the reinforcing Yang in Ophthalmology of TCM was retrieved from the China National Knowledge Infrastructure(CNKI),Wanfang Data,and VIP databases from January 1982 to September 2022.The search results were exported to NoteExpress software to remove duplicates and exclude irrelevant articles.The remaining literature information was entered into an Excel 2010 database.The prescription and medication rules of literatures from the database established were analyzed byTCM inheritance support platform after normalizing the Chinese medicines'names,four Qi,five flavors,and meridian tropism.RESULTS(1)General information:A total of 81 articles were included,involving 138 prescriptions and 168 different Chinese medicines,with a cumulative frequency of 1,350 times.(2)Prescription classification of five viscera:There were 12 categories,with the top five being spleen(42 times,30.43%),spleen and kidney(28 times,20.29%),kidney(24 times,17.39%),liver(16 times,11.59%),and heart(6 times,4.35%).(3)Frequency of prescription use:The top five prescriptions were Wuzhuyu Decoction(11 times,7.97%),Linggui Zhugan Decoction(9 times,6.52%),Buzhong Yiqi Decoction(8 times,5.80%),Shenqi Pill(7 times,5.07%)and Zhenwu Decoction(6 times,3.62%).(4)The properties of Chinese medicines:The most common medicine property were mainly warm(47 times,27.98%).Among the flavors,sweet Chinese medicines were the most common(69 times,41.07%),and spleen meridian was the most common attribution(40 times,23.81%).(5)High-Frequency Chinese medicines:The top five were poriacocos(71 times,5.26%),Atractylodes(68 times,5.04%),Astragalusmembranaceus(60 times,4.44%),Aconite(54 times,4.00%)and Cassia twig(51 times,3.78%).(6)Core Chinese medicine pairs:A total of 14 core Chinese medicine pairs were identified,among which the top five Chinese medicine pairs were Atractylodes-poriacocos、Astragalusmembranaceus-Atractylodes、Cassia twig-poriacocos、Atractylodes-Cassia twig、Astragalusmembranaceus-poriacocos.CONCLUSIONS The reinforcing Yang in the treatment of eye diseases often involves tonifying and assisting spleen,kidney,and liver Yang.However,it does not exclusively rely on warming and tonifying Yang Chinese medicines.It frequently combines tonifying Qi,damp-dispersing,and dispersing-wind Chinese medicines to nourish,protect,and promote the circulation of Yang Qi.This helps maintain the smooth flow of the visual system and facilitates the distribution of Yang Qi.The commonly used formulas and their combinations have distinct characteristics in the field of Ophthalmology of TCM.
作者
赖思艺
邱心悦
罗雨薇
刘光辉
LAI Siyi;QIU Xinyue;LUO Yuwei;LIU Guanghui(Fujian Principal People´s Hospital,Fujian University of Traditional Chinese Medicine,Fuzhou 350004,China)
出处
《中国中医眼科杂志》
2023年第10期926-931,共6页
China Journal of Chinese Ophthalmology
基金
福建中医药大学优势学科专项课题(X2022018-专项)。
关键词
扶阳法
中医眼科
规则分析
用药规律
中医传承辅助平台
reinforcing Yang
Ophthalmology of Traditional Chinese Medicine
rule analy⁃sis
using rules of Chinese medicines
Traditional Chinese Medicine inheritance support platform
