摘要
目的:探讨降钙素原(PCT)和血清淀粉样蛋白A(SAA)在重症肺炎(SP)诊疗中的价值。方法:选取65例肺炎患者,根据病情严重程度分为普通肺炎组33例和SP组32例,全部患者治疗前、治疗48 h后、治疗72 h后、出院前均接受PCT、SAA检测,对比两组各时点PCT、SAA水平差异,分析治疗前PCT、SAA在SP诊疗中的价值。结果:两组治疗48 h后、治疗72 h后、出院前,PCT、SAA水平均低于治疗前,但SP组治疗前、治疗48 h后、治疗72 h后、出院前PCT、SAA水平均高于普通肺炎组,两组比较差异有统计学意义(P<0.05);绘制ROC曲线发现,PCT、SAA单独检测及联合检测诊断SP的AUC>0.70,均有一定诊断价值。结论:PCT和SAA对SP有一定诊断价值。
Objective:To investigate the value of procalcitonin(PCT)and serum amyloid A(SAA)in the diagnosis and treatment of severe pneumonia(SP).Methods:The clinical data of 65 patients with pneumonia were retrospectively analyzed.The patients were divided into the common pneumonia group(33 cases)and SP group(32 cases)according to the severity of the disease.All patients received PCT and SAA tests before treatment,48 h after treatment,72 h after treatment and before discharge.The levels of PCT and SAA were compared between the two groups at each time point,and the value of PCT and SAA in the diagnosis and treatment of SP before treatment was analyzed.Results:After treatment of 48 h,72 h and before discharge,the levels of PCT and SAA in two groups were lower than those before treatment,but the levels of PCT and SAA in the SP group were higher than those in the common pneumonia group before treatment,48 h after treatment,72 h after treatment and before discharge,the difference was statistically significant(P<0.05).ROC curve was drawn,and it was found that the AUC of PCT and SAA alone and combined detection for SP were all over 0.70 before treatment,which had diagnostic value.Conclusion:PCT and SAA are valuable in diagnosis and treatment of SP.
作者
陈敏
简亚梅
徐亚军
曹清
李小芳
李永杰
CHEN Min;JIAN Yamei;XU Yajun;CAO Qing;LI Xiaofang;LI Yongjie(Central Hospital of Xinyu Iron&Steel Group Co.,LTD.,Xinyu 338000,China)
出处
《华夏医学》
CAS
2023年第4期62-66,共5页
Acta Medicinae Sinica
基金
新余市社会发展指导性科技计划项目(20213090917)。
