摘要
目的探究及比较不同孟鲁司特钠剂型在小儿哮喘患者中的用药依从性及接受度的影响。方法选取2022年5月至12月的160例支气管哮喘患儿为研究对象,将所有患儿对不同孟鲁司特钠剂型(颗粒、咀嚼片及口溶膜)的用药依从性(MARS-A量表)、儿童服药困难筛选调查问卷及接受度进行统计及比较,并比较不同性别及年龄患儿的评估结果。结果患儿对孟鲁司特钠口溶膜的用药依从性、儿童服药困难筛选调查问卷评估结果及接受度均显著优于颗粒及咀嚼片,差异有统计学意义(P<0.05)。不同年龄及性别患儿对孟鲁司特钠同种剂型的用药依从性、儿童服药困难筛选调查问卷评估结果及接受度比较,差异无统计学意义(P>0.05)。结论孟鲁司特钠口溶膜在小儿哮喘患者中的用药依从性及接受度相对更好,但不同性别及年龄患儿对同种剂型的差异并不显著,孟鲁司特钠口溶膜的应用可取性相对更高。
Objective To investigate and compare the influence of different dosage forms of montelukast sodium for drug compliance and acceptance of children with asthma.Methods 160 children with asthma from May 2022 to December 2022 were chosen as the research object,and the drug compliance(MARS-A scale),screening survey questionnaire for children with medication difficulties and acceptance of children for different dosage forms(granules,chewing tablets and oral thin films)of montelukast sodium were compared,and the evaluation results of children with different gender and ages were compared too.Results The drug compliance,evaluation results of the screening survey questionnaire for children with medication difficulties and acceptance of children for montelukast sodium oral thin films were significantly better than those of granules and chewing tablets,the differences were all statistically significant(P<0.05).The drug compliance,evaluation results of the screening survey questionnaire for children with medication difficulties and acceptance of children for the same dosage forms of montelukast sodium were compared,the differences were not statistically significant(P>0.05).Conclusion The drug compliance and acceptance of children with asthma for montelukast sodium oral thin films are relatively better,and the difference of children for different gender and ages were not significant,so its applicability of montelukast sodium oral thin films is relatively higher.
作者
简雷
朱英男
张星星
段传新
JIAN Lei;ZHU Yingnan;ZHANG Xingxing;DUAN Chanxin(Department of Otolaryngology,Maternal and Child Health Hospital of Hubei Province,Wuhan 430000,China)
出处
《中国医药指南》
2023年第27期6-9,共4页
Guide of China Medicine
关键词
孟鲁司特钠
小儿哮喘
颗粒
咀嚼片
口溶膜
用药依从性
接受度
Montelukast sodium
Children with asthma
Granules
Chewing tablets
Oral thin films
Drug compliance
Acceptance
