摘要
目的探讨不同护理干预措施对肾小球肾炎血液透析患者血清氧化应激指标的影响。方法选取2021年1月—2022年12月在商丘市中心医院接受血液透析治疗的肾小球肾炎患者60例,随机分为观察组和对照组,每组30例。对照组给予常规护理,观察组在此基础上加强入口部位、营养、心理、水电解质和酸碱平衡等方面的护理干预。比较两组患者治疗前后血清丙二醛(MDA)、超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-Px)和总抗氧化能力(T-AOC)的水平,以及并发症发生率、生活质量评分和满意度评分。结果两组患者治疗前各项指标比较差异无统计学意义(P>0.05)。治疗后,两组患者的MDA水平均降低,SOD、GSH-Px和T-AOC水平均升高,观察组的变化幅度大于对照组,差异有统计学意义(P<0.05)。观察组的并发症发生率(10.00%)低于对照组(26.67%),生活质量评分和满意度评分高于对照组,差异均有统计学意义(P<0.05)。结论不同护理干预措施可以降低肾小球肾炎血液透析患者的氧化应激水平,减少并发症发生,提高生活质量和满意度,值得临床推广应用。
Objective To investigate the effects of different nursing interventions on serum oxidative stress markers in patients with glomerulonephritis undergoing hemodialysis.Methods 60 patients with glomerulonephritis undergoing hemodialysis in Shangqiu Central Hospital from January 2021 to December 2022 were selected and randomly divided into an observation group and a control group,with 30 cases in each group.The control group received routine nursing care,while the observation group received enhanced nursing interventions in terms of access site care,nutrition,psychology,electrolyte balance,and acid-base balance,on the basis of routine care.The levels of serum malondialdehyde(MDA),superoxide dismutase(SOD),glutathione peroxidase(GSH-Px),and total antioxidant capacity(T-AOC)before and after treatment were compared between the two groups,as well as the incidence of complications,quality of life scores,and satisfaction scores.Results There was no significant difference in various indicators between the two groups before treatment(P>0.05).After treatment,the MDA level decreased and the levels of SOD,GSH-Px,and T-AOC increased in both groups,with greater changes in the observation group than in the control group,and the differences were statistically significant(P<0.05).The incidence of complications in the observation group(10.00%)was lower than that in the control group(26.67%),and the quality of life score and satisfaction score in the observation group were higher than those in the control group,with statistically significant differences(P<0.05).Conclusion Different nursing interventions can reduce the oxidative stress levels in patients with glomerulonephritis undergoing hemodialysis,decrease the incidence of complications,improve quality of life and satisfaction,and are worthy of clinical promotion and application.
作者
田秋月
张艳
袁留洁
TIAN Qiu-yue;ZHANG Yan;YUAN Liu-jie(Blood Purification Room,Shangqiu Central Hospital,Shangqiu,Henan,476000,China)
出处
《中国血液流变学杂志》
CAS
2023年第2期304-308,共5页
Chinese Journal of Hemorheology
关键词
肾小球肾炎
血液透析
护理干预
氧化应激
glomerulonephritis
hemodialysis
nursing intervention
oxidative stress
