摘要
目的探讨全身免疫炎症指数(SII)、Erasmus GBS呼吸功能不全评分(EGRIS)对吉兰-巴雷综合征(GBS)病人呼吸衰竭发生的预测价值。方法收集2018年5月至2021年5月在郴州市第一人民医院接受治疗的123例GBS病人的临床资料。根据是否发生呼吸衰竭分为呼吸衰竭组、非呼吸衰竭组。对比两组病人的EGRIS评分、SII;运用多因素logistic回归分析探究可能影响GBS病人呼吸衰竭的危险因素;使用受试者操作特征(ROC)曲线评估EGRIS、SII对GBS病人发生呼吸衰竭的预测价值。结果两组病人发病到住院时间[(5.3±0.6)d比(9.2±1.1)d]、EGRIS评分[(5.5±0.2)分比(2.8±0.3)分]及SII[(1683.6±64.3)分比(603.4±25.2分)]比较,差异有统计学意义(P<0.05)。EGRIS及SII是GBS病人发生呼吸衰竭的危险因素(OR值分别为1.43、5.26,均P<0.01)。EGRIS、SII及两者联合预测呼吸衰竭的曲线下面积分别为0.75、0.89、0.93,灵敏度分别为82.01%、96.67%、95.33%,特异度分别为69.01%、67.61%、78.87%。结论EGRIS、SII是预测GBS病人发生呼吸衰竭的指标,两者联合可准确预测呼吸衰竭风险。
Objective To investigate the predictive value of systemic immune inflammation index(SII)and Erasmus GBS respiratory insufficiency score(EGRIS)in the occurrence of respiratory failure in patients with Guillain-Barr'e syndrome(GBS).Methods The clinical data of 123 patients with GBS treated in the First People's Hospital of Chenzhou from May 2018 to May 2021 were collected.According to whether respiratory failure occurred,they were divided into respiratory failure group and non-respiratory failure group.The EGRIS score and SII between the two groups were compared.Multivariate logistic regression analysis was used to analyze the risk factors of respiratory failure.Receiver operator characteristic curve(ROC)was used to analyze the predictive value of EGRIS and SII on respiratory failure.Results There were significant differences in the time from onset to hospitalization[(5.3±0.6)d vs.(9.2±1.1)d],EGRIS score[(5.5±0.2)vs.(2.8±0.3)]and SII[(1683.6±64.3)vs.(603.4±25.2)]between two groups(P<0.05).EGRIS and SII were risk factors for respiratory failure in patients with GBS(OR values 1.43 and 5.26,respectively,P<0.01).The areas under the curve of EGRIS,SII and their combination in predicting respiratory failure were 0.75,0.89 and 0.93,respectively,the sensitivity were 82.01%,96.67%and 95.33%,respectively,and the specificity were 69.01%,67.61%and 78.87%,respectively.Conclusions EGRIS and SII are the indicators to predict respiratory failure in patients with GBS.The combination of EGRIS and SII can accurately predict the risk of respiratory failure.
作者
郭悦劼
谢勇
GUO Yuejie;XIE Yong(Department of Geriatric Medicine,the First People's Hospital of Chenzhou,Chenzhou,Hunan 423000,China)
出处
《安徽医药》
CAS
2023年第11期2241-2244,共4页
Anhui Medical and Pharmaceutical Journal
基金
湘南学院校级科研课题(2018XJ64)。
