摘要
目的 分析重组人表皮细胞生长因子(Recombinant human epidermal cell growth factor;rh-EGF)凝胶联合磺胺嘧啶银在烫伤创面修复中的临床应用效果。方法 回顾性分析2019年5月-2022年5月在本院门诊治疗的100例烫伤患儿的临床资料,根据其治疗方案不同分为2组。观察组50例应用重组人表皮细胞生长因子凝胶联合磺胺嘧啶银治疗,对照组50例应用重组人表皮细胞生长因子凝胶治疗,对两组患者的治疗结果进行比较。结果 观察组患者的换药次数少于对照组患者;且观察组无明显渗液渗出时间、创面完全愈合时间均更短(P<0.05)。随访3个月,观察组患儿烫伤创面血管、组织柔软性、色泽、瘢痕增生高度及总分显著低于对照组(P<0.05)。结论 重组人表皮细胞生长因子凝胶联合磺胺嘧啶银在烫伤创面修复中的能够缩短创面修复时间,并获得更高的美学效果,建议推广使用。
Objective To analyze Recombinant human epidermal cell growth factor(Recombinant human epidermal cell growth factor;Clinical effffect of rh-EGF gel combined with silver sulfadiazine in the repair of scald wounds.Methods Retrospective analysis of the clinical data of 100 scald patients treated in the outpatient department of our hospital from May 2019 to May 2022.They were divided into two groups according to their treatment methods.50 patients in the observation group were treated with recombinant human epidermal growth factor gel combined with silver sulfadiazine,and 50 patients in the control group were treated with recombinant human epidermal growth factor gel.The clinical outcomes of the two groups were studied and analyzed.Results The number of dressing changes in the observation group was less than the control group,and the time of no obvious exudation and the time of complete wound healing in the observation group were shorter than the control group(P<0.05).Follow up for 3 months showed that the blood vessels,tissue softness,color,hypertrophic scar height and total score of the scalded wound in the observation group were fisignificantly lower than the control group(P<0.05).Conclusion Recombinant human epidermal growth factor gel combined with silver ffsulfadiazine can shorten the wound repair time and obtain higher aesthetic effect in the repair of scalded wounds.It is recommended to promote its use.
作者
魏松
黄志见
殷炜
马周瑞
刘威
WEI Song;HUANG Zhi-jian;YIN Wei;MA Zhou-rui;LIU Wei(Department of Burn and Plastic Surgery,Children's Hospital of Soochow University,Jiangsu Province,215000,China)
出处
《中国医疗美容》
2023年第9期29-32,共4页
China Medical Cosmetology
关键词
重组人表皮细胞生长因子
磺胺嘧啶银
烫伤
儿童
recombinant human epidermal growth factor
silver sulfadiazine
scald wounds
children
