摘要
阐述了冰片通过破坏脂质层高度有序的脂质结构、破坏氢键网络以促渗的机理,介绍了冰片促进中药有效成分及化学药物透皮吸收的应用;重点总结了冰片作为天然成分添加至功效化妆品中的应用,介绍了其在色斑治疗、痤疮皮肤护理、湿疹皮肤护理、皮肤修护及抗氧化的效果。最后提出了冰片应用于化妆品中可能存在的问题,展望了其在化妆品开发领域的应用前景。
Borneol,as a traditional natural permeation enhancer,has been widely used to promote the transdermal absorption of active ingredients.In this review,the mechanism of borneol in promoting permeation by destroying the highly ordered lipid structure of the lipid layer and by destroying the hydrogen-bond network was described.The application of borneol in promoting the transdermal absorption of the active ingredients of traditional Chinese medicine and chemical drugs was introduced.The application of borneol as a natural ingredient added to functional cosmetics was summarized,and its effects on skin-spot treatment,acne skin care,eczema skin care,skin repair and anti-oxidation were introduced.Finally,the possible problems in the application of borneol in cosmetics were put forward,and the application prospect of borneol in development of cosmetics was given.
作者
许沅瑜
陈渝旭
张婧卿
王世东
赵志敏
杨得坡
徐新军
XU Yuan-yu;CHEN Yu-xu;ZHANG Jing-qing;WANG Shi-dong;ZHAO Zhi-min;YANG De-po;XU Xin-jun(College of Pharmacy,Sun Yat-sen University,Guangzhou,Guangdong 510006,China;Guangdong Yuansi South Pharmaceutical Biotechnology Co.,Ltd.,Meizhou,Guangdong 514699,China)
出处
《日用化学品科学》
CAS
2023年第10期57-60,共4页
Detergent & Cosmetics
关键词
冰片
促渗剂
化妆品
borneol
permeation enhancer
cosmetics