摘要
继发性甲状旁腺功能亢进(SHPT)是终末期肾病(ESKD)患者的常见并发症,主要特点是甲状旁腺激素(PTH)的升高。尽管肾移植是ESKD患者最有效的肾脏替代治疗方案,但PTH水平不仅影响移植肾本身,也与其合并症相关,而对肾移植前SHPT的治疗方法及时机仍存争议。本文将对肾移植前PTH水平对肾移植的影响、肾移植等待者的理想PTH水平和甲状旁腺切除术时机进行综述,以期对临床有参考意义。
Secondary hyperparathyroidism(SHPT)is a common complication in patients with end⁃stage kidney disease(ESKD).The main characteristic is elevated parathyroid hormone(PTH).Although kidney transplantation is the most effective replacement therapy for ESKD patients,the level of PTH in renal transplantation candidates not only affects the transplanted kidney itself,but also is associated with related complications.However,the treatment method and timing of SHPT before renal transplantation are still controversial.In this paper,we will review the influence of PTH level before kidney transplantation on kidney transplantation,ideal PTH level of kidney transplant recipients and timing of parathyroidectomy,to provide reference for clinical significance.
作者
张玉帅(综述)
边学海(审校)
ZHANG Yushuai;BIAN Xuehai(Department of Thyroid Surgery,China-Japan Union Hospital of Jilin University,Jilin Provincial Key Laboratory of Surgical Translational Medicine,Jilin Provincial Engineering Laboratory of Thyroid Disease Prevention and Control,Changchun 130033,China)
出处
《肾脏病与透析肾移植杂志》
CAS
CSCD
北大核心
2023年第4期388-393,共6页
Chinese Journal of Nephrology,Dialysis & Transplantation
