摘要
目的:探讨二白汤在帕金森病患者中的应用效果。方法:选取帕金森病患者60例,根据随机数字表法分为对照组(30例)和观察组(30例),对照组给予常规抗帕金森药物治疗,观察组在常规药物治疗基础上加服临床经验方二白汤,连续治疗30 d,比较两组治疗前、治疗后统一帕金森病评定量表(UPDRS)、HOEHN&YAHR分级评估量表、帕金森病生存质量量表(PDQ-39)和颤证中医证候评分。结果:观察组治疗后中医证候量表评分、UPDRS评分、PDQ-39评分显著低于本组治疗前,差异有统计学意义(P<0.05),H-Y量表评分低于本组治疗前,差异有统计学意义(P<0.05)。观察组治疗后中医证候量表评分、UPDRS评分显著低于对照组,差异有统计学意义(P<0.05),观察组治疗后PDQ-39评分低于对照组,差异有统计学意义(P<0.05),治疗后,两组H-Y量表评分差异无统计学意义(P>0.05)。结论:二白汤治疗帕金森病,在改善帕金森病患者的精神情绪、日常生活能力、运动功能、中医颤证证候等方面疗效明显。
Objective To explore the effect of Erbai decoction in patients with Parkinson's disease.Methods Select Parkinson's disease patients,60 patients were randomly divided into the control group(30 cases)and the treatment group(30 cases).The control group was treated with conventional anti Parkinson drugs,and the treatment group was treated with clinical experience formula Erbai Decoction on the basis of conventional drug treatment for 30 days.The two groups were compared with the Unified Parkinson's Disease Rating Scale(UPDRS),Hoehn&Yahr Scale,Parkinson's Disease Questionnaire(PDQ-39)and TCM syndrome score of tremor syndrome before and after treatment.Results The score of TCM syndrome scale,UPDRS and PDQ-39 of patients in the treatment group after treatment were significantly lower than those before treatment,the difference was statistically significant(P<0.05).The score of H-Y scale was lower than that before treatment,the difference was statistically significant(P<0.05).After treatment,the scores of TCM syndrome scale and UPDRS in the treatment group were significantly lower than those in the control group,with a statistically significant difference(P<0.05).After treatment,the PDQ-39 score in the treatment group were lower than those in the control group,with a statistically significant difference(P<0.05).After treatment,there was no statistically significant difference in H-Y scale score between the two groups(P>0.05).Conclusion Erbai decoction has obvious effect on improving the mental mood,daily living ability,motor function and TCM tremor syndrome of Parkinson's disease.
作者
李金容
舒建中
唐军
LI Jinrong;SHU Jianzhong;TANG Jun(Chongqing Traditional Chinese Medicine Hospital,Department ofEncephalopathy,Chongqing 400021,China)
出处
《中国民族民间医药》
2023年第19期108-112,共5页
Chinese Journal of Ethnomedicine and Ethnopharmacy
基金
2019年重庆市科研机构绩效激励引导专项项目(cstc2019jxjl130027)。
关键词
二白汤
帕金森病
统一帕金森病评定量表
帕金森病生存质量量表
Erbai Decoction
Parkinson's Disease
Unified Parkinson's Disease Rating Scale
Parkinson's Disease Questionnaire
