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慢性心力衰竭治疗口服药物的临床研究进展 被引量:1

Clinical research progress of oral drugs for chronic heart failure
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摘要 慢性心力衰竭是心血管疾病终末阶段,严重威胁人们生命健康,作为引起人类尤其是老年人死亡原因受到广泛关注。临床中对慢性心力衰竭治疗,主要是选择西医药物治疗方法,治疗药物包括强心苷类药物、利尿剂、血管扩张药物等,随着临床研究的不断深入,近年来出现的钠-葡萄糖共转运蛋白2(SGLT2)抑制剂、If通道阻滞剂、可溶性鸟苷酸环化酶(sGC)刺激剂等为心力衰竭患者带来了希望。不同的药物对于疾病干预作用存在差异,它们显示出一些积极的效果。本文针对治疗慢性心力衰竭药物研究及常用治疗药物的类型进行综述及评价,以指导临床中的合理用药参考。 Chronic heart failure is the final stage of cardiovascular disease,which is a serious threat to people's life and health,as a cause of death of human especially the elderly has been widely concerned.In clinical treatment of chronic heart failure,Western medicine is mainly selected,therapeutic drugs include strong cardioside drugs,diuretics,vascular dilator drugs,etc.With the continuous development of clinical research,the emergence of sodium-glucose cotransporter 2 inhibitors,if channel blockers,and soluble guanylate cyclase stimulators in recent years have brought hope to patients with heart failure.These different drugs have different intervention effects on the disease,showing some positive effects.In this paper,the research on drugs for the treatment of chronic heart failure and the types of drugs commonly used in patients were reviewed and evaluated,so as to guide clinical rational drug use.
作者 潘加欢 赵博文 胡罗霞 祁晨阳 毛威 Pan Jiahuan;Zhao Bowen;Hu Luoxia;Qi Chenyang;Mao Wei(The First Affiliated Hospital of Zhejiang Chinese Medical University,Hangzhou 310003,China;Zhejiang Hospital,Hangzhou 310013,China;Key Laboratory of Integrative Chinese and Western Medicine for the Diagnosis and Treatment of Circulatory Diseases of Zhejiang Province,Hangzhou 310053,China)
出处 《心脑血管病防治》 2023年第3期37-40,共4页 CARDIO-CEREBROVASCULAR DISEASE PREVENTION AND TREATMENT
关键词 慢性心力衰竭 治疗 口服药物 临床评价 Chronic heart failure Treatment Oral drugs Clinical evaluation
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