摘要
目的对适龄9~15岁女生母亲的宫颈癌知识、人乳头瘤病毒(HPV)疫苗知识和对不同HPV疫苗免费供应方案的选择意愿进行调查,为卫生行政部门制定相关免疫接种策略提供依据。方法于2022年10月通过“苏州预防接种”官方微信公众服务号向苏州市9~15岁女生母亲推送自行设计的问卷进行在线网络调查。结果共1648人参与调查,回收有效问卷1484份。如果政府开展适龄女生双价HPV疫苗免费接种项目,4种HPV疫苗免费供应方案选择人数由多至少依次为:699人(47.10%)选择方案二(免费接种中标国产双价HPV疫苗或自费补差价接种其他疫苗的方案)、565人(38.07%)选择方案一(采用参照二针国产双价HPV疫苗价格的现金补贴方案)、161人(10.85%)选择方案三(免费接种中标国产双价HPV疫苗或全自费接种其他疫苗的方案)和59人(3.98%)选择方案四(保证供应但纯自费接种方案)。不同学历(χ^(2)=53.77,P<0.05)、家庭月收入(χ^(2)=49.07,P<0.05)和认知得分(χ^(2)=8.19,P=0.04)对HPV疫苗免费供应方案的选择差异有统计学意义。多元logistics回归模型结果显示,相较于方案四,家庭月收入≤5000元是选择方案一(OR=5.65)、方案二(OR=5.31)和方案三(OR=14.34)的影响因素;选择方案一的影响因素还有家庭月收入10001~15000元(OR=2.59);方案三的影响因素还有月收入5001~10000元(OR=2.60)。在4种方案中选择接种九价疫苗的人均占比最多,分别为94.16%(532/565)、83.26%(582/699)、55.28%(89/161)和98.31%(58/59)。结论苏州市9~15岁女生母亲选择方案二的人数最多,家庭月收入和学历是HPV疫苗免费供应方案选择的影响因素。所有接种方案中家长对九价疫苗的选择最多,应尽快推进国产高性价比的九价HPV疫苗的研发、生产与供应。
Objective To investigate the knowledge on cervical cancer and human papillomavirus(HPV)vaccine,and intention choice of daughters′free HPV vaccination scheme among mothers of school-age girls for providing evidence to administrative departments in developing relevant vaccination strategies.Methods Using convenient sampling and a self-designed questionnaire,we conducted an online survey among 1648 mothers of girls aged 9-15 years through official WeChat website of Suzhou Vaccination during October 2022.The data collected from 1484 eligible respondents were statistically analyzed.Results Of the 1484 respondents for the four listed HPV vaccination schemes available to their daughters(including free domestic bivalent or subsidized HPV vaccine supplied by health administrative departments),699(47.10%)selected plan 2(free domestic bivalent HPV vaccine or partially subsidized vaccination of other HPV vaccines);565(38.07%)selected plan 1(with cash subsidy for other HPV vaccination according to the price of two-dose vaccination of domestic bivalent HPV vaccine);161(10.85%)selected plan 3(free vaccination of domestic HPV vaccine or self-paid vaccination of other HPV vaccines);and 59(3.98%)selected plan 4(self-paid vaccination of all other HPV vaccines available).Nine-valent HPV vaccine was the most frequently selected vaccine reported by the four groups of respondents with different intention choice of the vaccination scheme,with the selecting ratios of 94.16%,83.26%,55.28%,and 98.31%for the respondents reporting the intention choice of vaccination plan 2,1,3,and 4,respectively.The respondents'intention choice of daughters′free HPV vaccination scheme differed significantly by educational background(χ^(2)=53.77,P<0.05),monthly household income(χ^(2)=49.07,P<0.05),and the score of cognition on cervical cancer and HPV vaccine(χ^(2)=8.19,P=0.04).The results of multivariate logistic regression model showed that compared to those with a monthly household income of≥20001(Chinese Yuan),the respondents with a monthly household income of≤5000 were more likely to select the plan 1(odds ratio[OR]=5.65),plan 2(OR=5.31),and plan 3(OR=14.34)other than the plan 4;the respondents with a monthly household income of 10001-15000 were likely to select the plan 3(OR=2.59)other than the plan 4;and the respondents with a monthly family income of 5001-10000 were more likely to select the plan 3(OR=2.60)other than the plan 4.Conclusion In Suzhou city,about one half of the mothers of school-age girls intend to select free domestic bivalent vaccine or partially subsidized vaccination of other vaccines for their daughters′free HPV vaccination scheme,with nine-valent HPV vaccine being the most frequently selected vaccine,and the intention choice is mainly influenced by maternal monthly household income and education background.
作者
王天宇
邓景景
栾琳
徐娟
郑本锋
龚甜
张琢玉
张钧
WANG Tianyu;DENG Jingjing;LUAN Lin;XU Juan;ZHENG Benfeng;GONG Tian;ZHANG Zhuoyu;ZHANG Jun(School of Public Health,Nanjing Medical University,Nanjing 211166,China;Suzhou Center for Disease Control and Prevention,Suzhou 215004,China;Suzhou Maternal and Child Healthcare and Family Planning Service Center,Suzhou 215301,China)
出处
《中国公共卫生》
CAS
CSCD
北大核心
2023年第6期758-761,共4页
Chinese Journal of Public Health
基金
苏州市姑苏卫生人才计划(GSWS2021055)。
关键词
9~15岁女生
HPV疫苗
免费供应方案
苏州
girls aged 9-15 years
human papilloma virus vaccine
free vaccination scheme
Suzhou city
