摘要
随着2型糖尿病(T2DM)发病的普遍及人口老龄化的加重,肌肉减少症(肌少症)被更多的人所关注。通过研究的深入,发现肌少症与T2DM之间存在双向作用的关系。T2DM相关性肌少症可能与胰岛素抵抗、炎症、线粒体功能障碍等有关,由于其目前尚无根治方法,通过生活方式的干预及相应药物治疗为其主要的治疗方案。本文从T2DM相关性肌少症的发病机制及干预方式方面进行综述,并对其预防及治疗提供新的思路。
With the prevalence of type 2 diabetes mellitus(T2DM)and the increasing aging of population,more people pay attention to sarcopenia.Through in-depth research,it is found that there is a bidirectional relationship between sarcopenia and T2DM.T2DM related sarcopenia may be related to insulin resistance,inflammation,mitochondrial dysfunction,etc.Since there is no radical cure for it,lifestyle intervention and corresponding drug therapy are the main treatment options.This article reviews the pathogenesis and intervention methods of T2DM related sarcopenia,and provides new ideas for its prevention and treatment.
作者
武文艳
于苏国
刘曼
WU Wenyan;YU Suguo;LIU Man(Binzhou Medical University Hospital,Binzhou 256603,China;不详)
出处
《中国医学创新》
CAS
2023年第30期180-184,共5页
Medical Innovation of China
