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磁共振定量分析全肝脂质沉积分布规律

A Preliminary Study on the Distribution of Lipid Deposition in the Whole Liver of Magnetic Resonance Quantitative Analysis
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摘要 目的 运用水脂分离MRI成像技术定量测定全肝脏脂质含量,总结分析肝内脂质沉积分布一般性规律。方法 回顾性分析151例弥漫性脂肪肝患者MRI检查脂肪含量图,分别测量肝脏各段的脂肪分数值(HFF),将病例分成轻、中、重三个组;两两比较各段间及肝左右叶间HFF均值差异。结果 (1)轻、中、重度脂肪肝组HFF均值分别为:9.43%、15.57%、27.75%;组间差异均有统计学意义。(2)在轻度及中度脂肪肝组,肝左、右叶HHF均值差异有统计学意义;且肝右叶H H F均值大于肝左叶。(3)在中度脂肪肝组,尾状叶与其他区域间HFF差异有统计学意义;且尾状叶区域HFF均值小于其他区域。(4)在重度脂肪肝组中,肝脏各段间、叶间HFF均值差异无统计学意义。结论 在弥漫性脂肪肝轻中度组,肝内脂质沉积在肝右叶比左叶严重;而尾状叶脂质浸润较轻;在重度脂肪肝组,脂质在肝脏各处的沉积是相对较均匀的。临床工作中应选择测定肝右叶上段区域代表脂肪肝严重程度。 Objective A new technique was used to measure the lipid content in the whole liver,and the general rule of lipid deposition in the liver was summarized and analyzed.Methods 151 patients with diffuse fatty liver were analyzed retrospectively.Fat fraction(HFF)of liver segments was measured by 3D GRE MRI.The patients were divided into three groups:mild,moderate and severe The mean values of fat fraction between segments and between the left and right lobes of the liver were compared.Results(1)The mean values of HFF in mild,moderate and severe fatty liver groups were 8.43%,15.57%,27.75%,respectively(P<0.05).(2)In the mild and moderate fatty liver groups,the mean value of HHF in the left and right lobes of the liver was significantly different.The mean value of HHF in the right lobe was higher than that in the left lobe.(3)In moderate fatty liver group,HFF between caudate lobe and other regions was significantly different.The mean HFF in the caudate lobe region was smaller than that in other regions.(4)In the severe fatty liver group,there was no significant difference in the mean value of HFF between liver segments and lobes.Conclusion In the mild to moderate group,the lipid deposition in the right lobe was more severe than that in the left lobe,while the lipid infiltration in the caudate lobe was less severe.In the severe group,the lipid deposition in the liver was relatively uniform.
作者 梁卓栋 张嘉愉 LIANG Zhuo-dong;ZHANG Jia-yu(Department of Radiology,Jiangmen Central Hospital,Jiangmen 529400,Guangdong Province,China)
出处 《中国CT和MRI杂志》 2023年第10期128-129,共2页 Chinese Journal of CT and MRI
关键词 脂肪肝 磁共振 定量分析 Hepatic Steatosis Magnetic Resonance Imaging Quantitative Analysis
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