摘要
细胞焦亡是一种促炎性细胞程序性死亡,在非酒精性脂肪性肝炎发展中扮演重要角色。“痰湿瘀”互结于肝络是非酒精性脂肪性肝炎的核心病机,与细胞焦亡之间可能存在一定的内在联系。因此,通过细胞焦亡与“痰湿瘀”病机的微观联系,探讨中药治疗非酒精性脂肪性肝炎的作用机制,为中药治疗非酒精性脂肪性肝炎的作用机制研究提供新思路。
As a way of pro-inflammatory cell death,pyroptosis plays a role in the development of non-alcoholic steatohepatitis.The accumulation of phlegm,dampness and stasis in the liver is the core pathogenesis of non-alcoholic steatohepatitis,which may be associated with the pathogenesis of pyroptosis.Therefore,revealing the micro-connection of pyroptosis with phlegm,dampness and stasis to explore the mechanism of traditional Chinese medicine in the treatment of non-alcoholic steatohepatitis can provide new ideas for the treatment of this disease with integrated traditional Chinese and Western medicine.
作者
宋艺佳
刘鸣昊
赵文霞
SONG Yijia;LIU Minghao;ZHAO Wenxia(Henan University of Chinese Medicine,Zhengzhou 450000;The First Affiliated Hospital of Henan University of CM,Zhengzhou 450000,China)
出处
《世界中医药》
CAS
2023年第17期2480-2483,共4页
World Chinese Medicine
基金
国家自然科学基金项目(81904154)
河南省科技攻关计划项目(202102310168)。
关键词
非酒精性脂肪性肝炎
痰湿瘀
细胞焦亡
中医
病机
微观联系
治疗
中药
微观辨证
Non-alcoholic steatohepatitis
Phlegm,Dampness and stasis
Pyroptosis
Traditional Chinese medicine
Pathogenesis
Micro connection
Treatment
Chinese medicines
Micro syndrome differentiation
