摘要
目的研究有创机械通气序贯高流量湿化治疗在重症肺炎并呼吸衰竭治疗中的应用价值。方法选取2019年5月-2022年5月在我院诊治的80例重症肺炎并呼吸衰竭患者为研究对象,采用随机数字表法分为对照组(n=40)和观察组(n=40),对照组采用常规有创机械通气治疗,观察组采用有创机械通气序贯高流量湿化治疗。比较两组临床疗效、机械通气时间、ICU入住时间、血气指标[动脉血氧分压(PaO2)、动脉血二氧化碳分压(PaCO_(2))]、急性生理与慢性健康状况评分(APACHEⅡ)及并发症发生率。结果观察组治疗总有效率(95.00%)高于对照组(82.50%)(P<0.05);观察组机械通气时间、ICU入住时间短于对照组(P<0.05);观察组治疗后PaO2大于对照组,PaCO_(2)小于对照组(P<0.05);两组治疗后APACHEⅡ评分均低于治疗前,且观察组低于对照组(P<0.05);观察组并发症发生率为7.50%,低于对照组的20.00%(P<0.05)。结论采用有创机械通气序贯高流量湿化治疗重症肺炎并呼吸衰竭可有效改善患者血气指标,促进自主呼吸恢复,缩短机械通气和ICU入住时间,有效控制病情进展,且可降低并发症发生率。
Objective To study the application value of invasive mechanical ventilation and sequential high flow humidification therapy in severe pneumonia complicated with respiratory failure.Methods A total of 80 patients with severe pneumonia and respiratory failure diagnosed and treated in our hospital from May 2019 to May 2022 were selected as the research objects.They were divided into control group(n=40)and observation group(n=40)by random number table method.The control group was treated with conventional invasive mechanical ventilation,and the observation group was treated with invasive mechanical ventilation and sequential high flow humidification therapy.The clinical efficacy,mechanical ventilation time,ICU stay time,blood gas indexes[arterial partial pressure of oxygen(PaO_(2)),arterial partial pressure of carbon dioxide(PaCO_(2))],acute physiology and chronic health status score(APACHEⅡ)and complication rate were compared between the two groups.Results The total effective rate of treatment in the observation group(95.00%)was higher than that in the control group(82.50%)(P<0.05).The mechanical ventilation time and ICU stay time in the observation group were shorter than those in the control group(P<0.05).After treatment,PaO2 in the observation group was higher than that in the control group,and PaCO2 was lower than that in the control group(P<0.05).The APACHE II scores of the two groups after treatment were lower than those before treatment,and the observation group was lower than the control group(P<0.05).The incidence of complications in the observation group was 7.50%,which was lower than 20.00%in the control group(P<0.05).Conclusion Invasive mechanical ventilation and sequential high flow humidification in the treatment of severe pneumonia and respiratory failure can effectively improve the blood gas index,promote the recovery of spontaneous breathing,shorten the time of mechanical ventilation and ICU stay,effectively control the progress of the disease,and reduce the incidence of complications.
作者
王锐
WANG Rui(Department of Critical Care Medicine,Yiyang County People's Hospital,Yiyang 334400,Jiangxi,China)
出处
《医学信息》
2023年第21期82-85,共4页
Journal of Medical Information
关键词
有创机械通气
高流量湿化治疗
重症肺炎
呼吸衰竭
Invasive mechanical ventilation
High flow humidification therapy
Severe pneumonia
Respiratory failure
