摘要
目的在消毒供应中心实际工作情况下,验证压力蒸汽灭菌器灭菌程序脉动真空循环压强底值、脉动真空循环次数、慢升温阶段开始温度3个变量对蒸汽穿透管腔构造效果的影响。方法使用穿透难度依次递增的管腔灭菌过程挑战装置(PCD)的组合套装,通过调整灭菌程序的多项参数来观察管腔PCD组合中化学指示物的通过情况,评价不同程序的蒸汽穿透性能。结果降低真空循环压强底值能有效提高蒸汽对管腔的穿透效果;在缩短抽真空与蒸汽注入时间的前提下,增加循环次数对穿透结果影响并不显著;慢升温阶段开始温度为128℃及130℃时,蒸汽穿透效果无明显区别,在升至132℃时蒸汽穿透效果出现明显下降。结论压力蒸汽灭菌程序的参数设置对含腔体构造的复杂器械的蒸汽穿透效果与灭菌结果影响很大,应结合科室实际情况与所需处理器械的复杂性调整合适的灭菌程序,确保器械的无菌质量。
Objective To verify the impact of three variables,namely the bottom value of pulsating vacuum cycle pressure,the number of pulsating vacuum cycles,and the starting temperature of the slow heating stage,of sterilization program of the pressure steam sterilizer on the steam penetration effect in tube cavity structure under the actual working conditions of CSSD.Methods Using a combination set of luminal sterilization process challenge device(PCD)with increasing penetration difficulty,the passage of chemical indicators in the luminal PCD was observed by adjusting multiple parameters of the sterilization program to evaluate the steam penetration performance of different programs.Results Reducing the bottom value of vacuum cycle pressure could effectively improve the steam penetration effect in tube cavity,and there was no significant difference in the steam penetration effect by increasing the number of cycles on the premise of shortening the time of vacuum pumping and steam injection.There was no significant difference in the steam penetration effect when the starting temperature of the slow heating stage was 128℃and 130℃,and the steam penetration effect showed a significant decrease when the starting temperature reached 132℃.Conclusions The parameter setting of the pressure steam sterilization program has a great impact on the steam penetration effect and sterilization results of complex instruments with cavity structures.It is necessary to adjust the appropriate sterilization program based on the actual situation of the department and the complexity of the instruments to ensure the sterile quality of the instruments.
作者
赵清
郭威
张兴华
李进
易敏
苏裕心
严士玲
ZHAO Qing;GUO Wei;ZHANG Xing-hua;LI Jin;YI Min;SU Yu-xin(Sichuan Academy of Medical Sciences&Sichuan Provincial People’s Hospital&Affiliated Hospital of UESTC,Chengdu Sichuan 610072;Beijing GKE Science and Technology Co.,Ltd.;China Food and Drug Enterprise Quality and Safety Promotion Association,China)
出处
《中国消毒学杂志》
CAS
2023年第10期771-775,共5页
Chinese Journal of Disinfection
关键词
压力蒸汽灭菌
过程挑战装置
蒸汽穿透效果
pressure steam sterilization
process challenge device
steam penetration effect
