摘要
目的:分析评估老年焦虑症伴睡眠障碍患者于治疗期间联合应用米氮平、重复经颅磁刺激的效果,评估对患者心理状态以及睡眠质量所产生的影响。方法:选取2022年1月至2022年12月宁德市康复医院收治的老年焦虑症伴睡眠障碍患者60例作为研究对象,按照随机数字表法分为对照组和观察组,每组30例。对照组治疗期间单独应用米氮平,观察组联合应用米氮平、重复经颅磁刺激,对比2组患者睡眠质量,包括匹兹堡睡眠质量指数(PSQI评分),焦虑评分包括焦虑自评量表(SAS)、汉密尔顿焦虑量表(HAMA),并发症发生率。结果:观察组PSQI评分各评估项目均低于对照组,差异均有统计学意义(均P<0.05)。干预前,对比分析2组患者SAS、HAMA评分,差异均无统计学意义(均P>0.05);观察组治疗后SAS、HAMA评分较低于对照组,差异均有统计学意义(均P<0.05)。观察组患者并发症发生率低于对照组,差异有统计学意义(P<0.05)。结论:伴有睡眠障碍的老年焦虑症患者在治疗期间联合应用米氮平、重复经颅磁刺激对于缓解焦虑症状以及改善睡眠质量具有突出效果,具有较高的安全性。
Objective:To analyze and evaluate the effect of combined Mirtazapine and repetitive transcranial magnetic stimulation(TMS)on the psychological status and sleep quality of elderly patients with anxiety and sleep disorder during treatment.Methods:The case data of this study was collected from January 2022 to December 2022.All the enrolled subjects were diagnosed with senile anxiety disorder with sleep disorder.A total of 60 patients were screened and divided into control group and observation group by random number table method.The control group was treated with Mirtazapine alone during the treatment period,and the observation group was treated with Mirtazapine and repetitive transcranial magnetic stimulation.The sleep quality(PSQI score),anxiety scores(SAS,HAMA scores)and incidence of complications were compared.Results:The PSQI scores of the observation group were lower than those of the control group in all evaluation items(P s<0.05).Before intervention,there was no significant difference in SAS and HAMA scores between the two groups of patients(P s>0.05).The SAS and HAMA scores of the observation group after treatment were lower than those of the control group(P s<0.05).The incidence of complications in the observation group was lower than that in the control group,and the comparison results showed statistical differences(P<0.05).Conclusion:The combination of Mirtazapine and repetitive transcranial magnetic stimulation in the treatment of elderly anxiety patients with sleep disorder has a prominent effect on alleviating anxiety symptoms and improving sleep quality,with high safety.
作者
陆东曦
LU Dongxi(Department of Male,Ningde Rehabilitation Hospital Second,Ningde 352100,China)
出处
《世界睡眠医学杂志》
2023年第7期1546-1548,共3页
World Journal of Sleep Medicine
关键词
米氮平
重复经颅磁刺激
伴睡眠障碍
老年焦虑症
Mirtazapine
Repetitive transcranial magnetic stimulation
With Sleep disorder
Elderly anxiety disorder
