摘要
帕金森病(PD)便秘一定程度上可加速PD的进展。治疗便秘能够明显改善PD患者的生活质量,并可能延缓PD的进展。目前,针灸治疗PD便秘的机制研究尚处于起步阶段,主要围绕神经体液因子、肠道菌群及细菌发酵产物、肠道炎性反应等方面进行研究,存在研究干预方法单一、研究思维局限、学科间合作不足等问题。本文通过系统梳理针灸治疗PD便秘的机制研究进展,以期为后续研究提供参考。
Constipation may accelerate the progression of Parkinson’s disease(PD).The quality of life in PD patients can be significantly improved when constipation is treated,hence the disease progression may be delayed.At present,the mechanism research is still at the initial stage for acupuncture in treatment of PD,focusing on neurohu⁃moral factors,intestinal flora,bacterial fermentation products and intestinal inflammation;and there are the problems such as single intervention,thinking limitation and insufficient cooperation among disciplines.This paper systematically reviews the mechanism research progress of acupuncture for the treatment of constipation in PD so as to provide the references for the subsequent studies.
作者
李奕萱
韩家浩
李苗苗
张涛
LI Yi-xuan;HAN Jia-hao;LI Miao-miao;ZHANG Tao(Beijing Key Laboratory for Acupuncture-Moxibustion Neuro-modulation,Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University,Beijing 100010,China;Department of Chinese Medicine,Community Healthcare Center of Shangzhuang Town,Haidian District,Beijing 100053;Centre of Integrated Chinese and Western Medicine,Beijing You’an Hospital Affiliated to Capital Medical University,Beijing 100069;Department of Chinese Medicine,Beijing Mentougou District Hospital of Traditional Chinese Medicine,Beijing 102300;Department of Brain Disease and Diabetics,Inner Mongolia Hospital Affiliated to Beijing Hospital of Traditional Chinese Medicine,Bayannur,Inner Mongolia Autonomous Region 015099)
出处
《针刺研究》
CAS
CSCD
北大核心
2023年第10期1055-1061,共7页
Acupuncture Research
基金
国家自然科学基金青年基金项目(No.82004443)
北京市科学技术协会2021-2023年度青年人才托举工程。
关键词
帕金森病
便秘
针灸
机制研究进展
Parkinson’s disease
Constipation
Acupuncture-moxibustion
Progress of mechanism research