摘要
目的探讨膝关节痛风性关节炎患者应用能谱CT联合MRI检查的影像学特征与不同血尿酸(SUA)水平之间的相关性。方法回顾2021年3月至2022年3月台州市中心医院诊治的80例膝关节痛风性关节炎患者的临床资料,均行能谱CT联合MRI检查,并检测SUA水平,分析不同SUA水平(A组420~<480μmol/L、B组480~<540μmol/L、C组540~<600μmol/L、D组≥600μmol/L)患者的影像学特征检出率,以及影像学特征与不同SUA水平的相关性。结果经能谱CT联合MRI检查发现,表现为关节腔积液征象的患者数量最多,为74例,占92.50%;其次为软组织肿胀、滑膜增生等,表现为骨髓水肿征象的患者数量最少,为33例,占41.25%。不同SUA水平患者在痛风石、骨侵蚀方面检出率的差异均有统计学意义(均P<0.05),而在骨髓水肿、滑膜增生、软组织肿胀、关节腔积液方面检出率的差异均无统计学意义(均P>0.05)。经Pearson相关分析发现,膝关节痛风性关节炎患者SUA水平与痛风石、骨侵蚀检出率均呈正相关(r=0.702、0.714,均P<0.05)。结论膝关节痛风性关节炎患者应用能谱CT联合MRI检查发现,SUA水平与痛风石和骨侵蚀的检出率呈正相关,能够为临床诊疗提供相应参考。
Objective To investigate the imaging characteristics of energy spectrum CT combined with magnetic resonance imaging(MRI)in knee gouty arthritis patients with different levels of serum uric acid(SUA).Methods The clinical data of 80 patients with gouty arthritis of the knee joint diagnosed and treated at Taizhou Central Hospital from March 2021 to March 2022 were retrospectively analyzed.All patients underwent energy spectrum CT combined with MRI examination.According to SUA levels patients were divided into four groups:group A(420-<480μmol/L),group B(480-<540μmol/L),group C(540-<600μmol/L)and group D(≥600μmol/L).The association between imaging characteristics and different levels of SUA was analyzed.Results On the energy spectrum CT and MRI imaging the joint cavity effusion was detected the most frequently,74 cases(92.50%),followed by soft tissue swelling,synovial hyperplasia,while the detection of bone marrow edema was the least,33 cases(41.25%).There were significant differences in imaging detection of gout stone and bone erosion among patients with different levels of SUA(all P<0.05),but no significant difference in imaging signs of bone marrow edema,synovial hyperplasia,soft tissue swelling,and joint cavity effusion(all P>0.05).Pearson correlation test showed that the SUA level in patients with gouty arthritis of the knee was positively correlated with the detection rate of gout stone and bone erosion(r=0.702,0.714,both P<0.05).Conclusion In patients with knee gouty arthritis undergoing energy spectrum CT combined with MRI examination,the SUA levels are positively correlated with the detection rate of gout stone and bone erosion,which may provide reference for clinical diagnosis and treatment.
作者
徐祖良
刘红宇
汪国余
施一鸣
李春胜
XU Zuliang;LIU Hongyu;WANG Guoyu;SHI Yiming;LI Chunsheng(Department of Radiology,Taizhou Central Hospital,Taizhou 318000,China;不详)
出处
《浙江医学》
CAS
2023年第20期2158-2162,共5页
Zhejiang Medical Journal
关键词
膝关节
痛风性关节炎
能谱CT
MRI
血尿酸
Knee
Gouty arthritis
Energy spectrum CT
Magnetic resonance imaging
Serum uric acid
