摘要
目的:探讨与分析超声三维斑点技术联合SYNTAX评分对冠心病病情的判断价值。方法:2022年2月到2023年1月选择在医院诊治的冠心病患者350例作为研究对象,所有患者都给予超声三维斑点检查,同时所有患者都给予SYNTAX评分。随访记录患者的主要不良心血管事件(MACE)发生情况病进行相关性分析。结果:在350例患者中,随访到2023年2月1日,平均随访时间为9.14±1.13个月,发生MACE45例(MACE组),占比12.9%,其中心源性死亡6例、冠脉综合征14例、血运重建13例、恶性心律失常7例、心力衰竭5例。MACE组的年龄、体重指数、性别、总胆固醇(TG)、高密度脂蛋白(HDL-C)、低密度脂蛋白(LDL-C)、甘油三酯(TC)血糖与非MACE组对比无显著差异(P>0.05)。MACE组的超声三维斑点参数-右室收缩峰值应变率(SRs)高于非MACE组(P<0.05),右室舒张晚期峰值应变率(SRa)、舒张早期峰值应变率(SRc)与非MACE组对比有显著降低(P<0.05)。MACE组的SYNTAX评分明显高于非MACE组(P<0.05),两组的SYNTAX评分分级人群占比也有显著差异(P<0.05)。在350例患者中,Spearsman分析显示SYNTAX评分、SRs、SRc、SRa都与MACE的发生呈现正相关性(P<0.05)。logistic回归分析法显示SYNTAX评分、SRs、SRc、SRa都为导致MACE发生的重要因素(P<0.05)。结论:冠心病患者治疗后MACE的发生率依然比较高,多伴随有SYNTAX评分增高,超声三维斑点技术检查也存在一定的差异性,超声三维斑点技术联合SYNTAX评分能有效反映冠心病患者的病情。
Objective:To explore and analysis the values of three-dimensional ultrasound speckle technique combined with SYNTAX score in the diagnosis of coronary heart disease.Methods:From February 2022 to January 2023,350 cases of patients with coronary heart disease diagnosed and treated in a certain hospital were selected as the study subjects.All patients were given three-dimensional ultrasound spot examination,and all patients were given SYNTAX score.The incidence of major adverse cardiovascular event(MACE)of the patients were followed up and recorded for correlation analysis.Results:In the 350 patients,the average follow-up time were 9.14±1.13 months until February 1,2023.There were 45 cases of MACE(MACE group),accounting for 12.9%,included 6 cases of cardiac death,14 cases of coronary syndrome,13 cases of revascularization,7 cases of malignant arrhythmia,and 5 cases of heart failure.There were no significant difference in age,body mass index,sex,total cholesterol(TG),high-density lipoprotein(HDL-C),low density lipoprotein(LDL-C),triglyceride(TC)blood glucose compared between MACE group and non-MACE group(P>0.05).The three-dimensional ultrasound speckle parameter-right ventricular systolic peak strain rate(SRs)in the MACE group were higher than that in the non-MACE group(P<0.05),and the right ventricular late diastolic peak strain rate(SRa)and early diastolic peak strain rate(SRc)were significantly lower than those in the non-MACE group(P<0.05).The SYNTAX scores of the MACE group were significantly higher than that of the non-MACE group(P<0.05),and there were also significant difference in the proportion of people in the SYNTAX score grading compared between the two groups(P<0.05).In the 350 patients,Spearman analysis showed that SYNTAX score,SRs,SRc and SRa were positively correlated with the occurrence of MACE(P<0.05).Logistic regression analysis showed that SYNTAX score,SRs,SRc and SRa were important factors leaded to MACE(P<0.05).Conclusion:The incidence of MACE in patients with coronary heart disease after treatment is still relatively high,which is often accompanied by the increase of SYNTAX score.There are certain differences in the examination of three-dimensional ultrasound speckle technology.The combination of three-dimensional ultrasound speckle technology and SYNTAX score can effectively reflect the condition of patients with coronary heart disease.
作者
丁冰倩
茅卫卫
陈娟
王佳玲
陈小丽
DING Bing-qian;MAO Wei-wei;CHEN Juan;WANG Jia-ling;CHEN Xiao-li(Cardiac ultrasound room,The Second Affiliated Hospital of Nantong University,Nantong,Jiangsu,226000,China;Department of Cardiovascular Medicine,The Second Affiliated Hospital of Nantong University,Nantong,Jiangsu,226000,China)
出处
《现代生物医学进展》
CAS
2023年第18期3564-3567,3581,共5页
Progress in Modern Biomedicine
基金
江苏省卫健委老年健康科研项目(LKM2022060)。
关键词
超声三维斑点技术
SYNTAX评分
冠心病
Three-dimensional ultrasound speckle technology
SYNTAX score
Coronaryheart disease