摘要
目的了解北京市6~17岁儿童铁储量(body iron,BI)水平和分布。方法于2016—2017年采用多阶段分层整群随机抽样方法对北京市1392名6~17岁儿童进行问卷调查和体格检查,采集空腹静脉血,采用免疫比浊法测定血清铁蛋白(serum ferritin,SF)和血清运铁蛋白受体(serum soluble transferrin receptor,sTfR),计算BI,评估6~17岁儿童BI状况。结果北京市6~17岁儿童BI水平为(5.49±2.94)mg/kg,男童高于女童,腹型肥胖者高于非腹型肥胖者(P<0.05)。BI浓度4~7.99 mg/kg占比最高(57.3%),<0 mg/kg占比最低(4.3%);不同性别、不同年龄及是否腹型肥胖者之间BI浓度构成比差异均有统计学意义(P<0.05)。贫血患病率为2.7%(95%CI 1.9~3.6),低铁蛋白(SF<25μg/L)率为22.5%(95%CI 20.0~24.8),铁缺乏(SF<15μg/L)率7.8%(95%CI 6.4~9.3),铁储量负态(BI<0 mg/kg)率为4.3%(95%CI 3.2~5.3);贫血率、低铁蛋白率、铁缺乏率和铁储量负态率均女童高于男童、12~17岁高于6~11岁(P<0.01)。结论2016—2017年北京市6~17岁儿童仍存在铁缺乏,女童和12~17岁儿童BI低水平比例较多。
OBJECTIVE To quantitatively assess the concentration and distribution of body iron(BI)in children aged 6 to 17 years in Beijing.METHODS A total of 1392 children aged 6 to 17 years in Beijing were randomly selected for questionnaire survey and physical examination in 2016-2017.Fasting venous blood was collected,serum ferritin(SF)and serum soluble transferrin receptor(sTfR)were measured by immunoturbidimetric assay.BI were calculated,and the concentration and distribution of BI in children aged 6 to 17 years was assessed.RESULTS The average BI level of children aged 6 to 17 in Beijing was(5.49±2.94)mg/kg.The average BI level of boys was higher than that of girls,and the average BI level of children with abdominal obesity was higher than that of children without abdominal obesity,and the differences were statistically significant(P<0.05).The concentration of BI in children aged 6 to 17 years in Beijing was 4-7.99 mg/kg,accounting for the highest proportion(57.3%).The concentration of BI<0 mg/kg accounted for the lowest proportion(4.3%).There were significant differences in the distribution of BI concentration in different gender,age and abdominal obesity(P<0.05).The anemia rate of children aged 6 to 17 in Beijing was 2.7%(95%CI 1.9-3.6),the low ferritin rate(SF<25μg/L)was 22.5%(95%CI 20.0-24.8),and the iron deficiency rate(SF<15μg/L)was 7.8%(95%CI 6.4-9.3),the negative iron stores(BI<0 mg/kg)rate was 4.3%(95%CI 3.2-5.3).The anemia rate,low ferritin rate,iron deficiency rate and negative iron stores rate were higher in girls than boys,and higher in children aged 12 to 17 years than in children aged 6 to 11 years,and the differences were statistically significant(P<0.01).CONCLUSION Iron deficiency was still present in children aged 6 to 17 in Beijing from 2016 to 2017.The proportion of low BI level in girls and children aged 12 to 17 is higher,respectively.
作者
黄梨煜
于博
沙怡梅
姚一泓
屠瑞莹
赵耀
Huang Liyu;Yu Bo;Sha Yimei;Yao Yihong;Tu Ruiying;Zhao Yao(Beijing Center for Disease Control and Prevention,Beijing 100013,China;Beijing Fangshan District Center for Disease Control and Prevention,Beijing 102401,China)
出处
《卫生研究》
CAS
CSCD
北大核心
2023年第6期924-929,共6页
Journal of Hygiene Research
